Results 171 to 180 of about 309,089 (339)

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Establishment of mouse induced pluripotent stem cells selected for Nanog expression

, 2008
Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka   +2 more
openalex   +2 more sources

Tumorigenicity of Human Induced Pluripotent Stem Cells Depends on the Balance of Gene Expression Between P21 and P53 [PDF]

, 2009
Hisashi Moriguchi, Raymond T. Chung, Chifumi Sato   +2 more
openalex   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Transfusion therapy by blood platelets derived from embryonic stem cells or induced pluripotent stem cells

, 2008
Koji Eto, Hiromitsu Nakauchi
openalex   +2 more sources

Induced pluripotent stem cells free of exogenous reprogramming factors [PDF]

, 2009
Ramzey Abujarour, Sheng Ding
openalex   +1 more source

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

Science, 2008
K. Okita, M. Nakagawa, Hong Hyenjong, T. Ichisaka, S. Yamanaka   +4 more
semanticscholar   +1 more source

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

Advanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa   +7 more
wiley   +1 more source

Research progress and application prospect of induced pluripotent stem cells

, 2008
Guoqiang Liu, Tianpei Hong
openalex   +1 more source

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

Nature, 2009
K. Woltjen, Iacovos P. Michael, P. Mohseni, R. Desai, M. Mileikovsky, R. Hämäläinen, R. Cowling, Wei Wang, Pentao Liu, M. Gertsenstein, K. Kaji, H. Sung, A. Nagy   +12 more
semanticscholar   +1 more source