Results 261 to 270 of about 496,668 (364)

Modeling ALS with motor neurons derived from human induced pluripotent stem cells

Nature Neuroscience, 2016
S. Sances, L. Bruijn, S. Chandran, K. Eggan, Ritchie Ho, Joseph R. Klim, M. Livesey, Emily R. Lowry, J. D. Macklis, D. Rushton, Cameron Sadegh, D. Sareen, H. Wichterle, Su-Chun Zhang, C. Svendsen   +14 more
semanticscholar   +1 more source

5‐Aza combined with VPA reprograms human T lineage acute leukemia Jurkat cells into B‐cell‐like cells by epigenetic activation of PAX5

Biotechnology Progress, EarlyView.
Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi, Guoxu Zheng, Xu Chen, Baile Zuo, Wei Wang, Yufang Li, Chunmei Zhang, Jie Chu, Xiuli Mu, Weihong Wen, Tao Wang, An‐Gang Yang   +11 more
wiley   +1 more source

Expansion of induced pluripotent stem cells under consideration of bioengineering aspects: part 1. [PDF]

Appl Microbiol Biotechnol
Schneider SL, Teale MA, Seidel S, Krasenbrink J, Poggel M, Eibl D, Sousa MFQ, Eibl R.   +7 more
europepmc   +1 more source

Application of induced pluripotent stem (iPS) cells in periodontal tissue regeneration [PDF]

, 2010
Xuejing Duan, Qisheng Tu, Jin Zhang, Jinhai Ye, Cesar Sommer, Gustavo Mostoslavsky, David L. Kaplan, Pishan Yang, Jake Y. Chen   +8 more
openalex   +1 more source

Cryopreservation practices in clinical and preclinical iPSC‐based cell therapies: Current challenges and future directions

Biotechnology Progress, EarlyView.
Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin, Geoffrey Toner, Ronald Kander   +2 more
wiley   +1 more source

Expansion of induced pluripotent stem cells under consideration of bioengineering aspects: part 2. [PDF]

Appl Microbiol Biotechnol
Teale MA, Schneider SL, Seidel S, Krasenbrink J, Poggel M, Eibl D, Sousa MFQ, Eibl R.   +7 more
europepmc   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

CD157⁺ vascular endothelial cells derived from human-induced pluripotent stem cells have high angiogenic potential. [PDF]

Inflamm Regen
Takii A, Tanabe Y, Li W, Shiomi H, Inoue A, Muramatsu F, Jia W, Takakura N.   +7 more
europepmc   +1 more source

Feeder- and serum-free establishment and expansion of human induced pluripotent stem cells

, 2009
Mehdi Totonchi, Adeleh Taei, Ali Seifinejad, Mohammadsharif Tabebordbar, Hassan Rassouli, Ali Farrokhi, Hamid Gourabi, Nasser Aghdami, Ghasem Hosseini Salekdeh, Hossein Baharvand   +9 more
openalex   +2 more sources

Molecular Analyses of Human Induced Pluripotent Stem Cells and Embryonic Stem Cells [PDF]

, 2010
Mark H. Chin, Matteo Pellegrini, Kathrin Plath, William E. Lowry   +3 more
openalex   +1 more source