Results 281 to 290 of about 496,668 (364)

Effect of Octacalcium Phosphate on Osteogenic Differentiation of Induced Pluripotent Stem Cells in a 3D Hybrid Spheroid Culture. [PDF]

Biomimetics (Basel)
Sugai Y, Hamai R, Shiwaku Y, Anada T, Tsuchiya K, Kimura T, Tadano M, Yamauchi K, Takahashi T, Egusa H, Suzuki O.   +10 more
europepmc   +1 more source

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Cell, 2009
F. Soldner, D. Hockemeyer, C. Beard, Qing Gao, G. Bell, Elizabeth G. Cook, G. Hargus, A. Blak, O. Cooper, M. Mitalipova, O. Isacson, R. Jaenisch   +11 more
semanticscholar   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Differentiation of human hyalocytes from induced pluripotent stem cells through ascorbic acid treatment. [PDF]

Hum Cell
Mazzoldi EL, Benini G, Ferraro RM, Micheletti M, Martellosio G, Balduchelli V, Sacristani P, Lussignoli D, Semeraro F, Rezzola S, Presta M, Bergandi L, Meduri A, Giliani SC.   +13 more
europepmc   +1 more source

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip

Nature Protocols, 2018
Samira Musah, Nikolaos Dimitrakakis, Diogo M. Camacho, G. Church, D. Ingber   +4 more
semanticscholar   +1 more source

FABP7 Expression Modulates the Response of Astrocytes to Induced Endotoxemia

Glia, EarlyView.
FABP7 silencing reduces inflammatory response in astrocytes. FABP7 silencing decreases astrocyte‐mediated neurotoxicity. FABP7 silencing attenuates NF‐κB‐dependent transcriptional response during endotoxemia. ABSTRACT Fatty acid binding proteins (FABPs) are a family of small proteins involved in fatty acid (FA) subcellular trafficking.
Mariana Bresque, Daniel Esteve, Garret Balmer, Haylee L. Hamilton, Joshua S. Stephany, Mariana Pehar, Marcelo R. Vargas   +6 more
wiley   +1 more source

Genome-Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells. [PDF]

Adv Sci (Weinh)
Zhu X, Huang L, Li G, Deng B, Wang X, Yang H, Zhang Y, Wen Q, Wang C, Zhang J, Zhao Y, Li K, Liu Y.   +12 more
europepmc   +1 more source

Influence of donor age on induced pluripotent stem cells

Nature Biotechnology, 2016
Valentina Lo Sardo, William Ferguson, G. Erikson, E. Topol, K. Baldwin, A. Torkamani   +5 more
semanticscholar   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

A Cross-Linked Cyclosiloxane Polymer Matrix as a Platform Enabling Long-Term Culture of Human Induced Pluripotent Stem Cells with Naïve-Like Features. [PDF]

Biomater Res
Seo C, Song J, Choi Y, Kim T, Lee D, Jon S.   +5 more
europepmc   +1 more source