Results 31 to 40 of about 496,668 (364)

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

Stem cell research & therapeutics, 2017
BackgroundOsteoarthritis (OA) is the most common joint disease worldwide. In the past decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA.
Yu Zhu, Yuchen Wang, Bizeng Zhao, X. Niu, Bin Hu, Qing Li, Juntao Zhang, Jian Ding, Yunfeng Chen, Yang Wang   +9 more
semanticscholar   +1 more source

Neural Stem Cells and Methods for Their Generation From Induced Pluripotent Stem Cells in vitro

Frontiers in Cell and Developmental Biology, 2020
Neural stem cells (NSCs) provide promising approaches for investigating embryonic neurogenesis, modeling of the pathogenesis of diseases of the central nervous system, and for designing drug-screening systems.
A. A. Galiakberova, E. Dashinimaev
semanticscholar   +1 more source

Establishment of Bovine-Induced Pluripotent Stem Cells [PDF]

International Journal of Molecular Sciences, 2021
Pluripotent stem cells (PSCs) have been successfully developed in many species. However, the establishment of bovine-induced pluripotent stem cells (biPSCs) has been challenging. Here we report the generation of biPSCs from bovine mesenchymal stem cells (bMSCs) by overexpression of lysine-specific demethylase 4A (KDM4A) and the other reprogramming ...
Yue Su, Ling Wang, Zhiqiang Fan, Ying Liu, Jiaqi Zhu, Deborah Kaback, Julia Oudiz, Tayler Patrick, Siu Pok Yee, Xiuchun (Cindy) Tian, Irina Polejaeva, Young Tang   +11 more
openaire   +2 more sources

Organoids in domestic animals: with which stem cells?

Veterinary Research, 2021
Organoids are three-dimensional structures that are derived from the self-organization of stem cells as they differentiate in vitro. The plasticity of stem cells is one of the major criteria for generating organoids most similar to the tissue structures ...
Bertrand Pain
doaj   +1 more source

Defining the Pluripotent Marker Genes for Identification of Teleost Fish Cell Pluripotency During Reprogramming

Frontiers in Genetics, 2022
Pluripotency is a transient state in early embryos, which is regulated by an interconnected network of pluripotency-related genes. The pluripotent state itself seems to be highly dynamic, which leads to significant differences in the description of ...
Huajin Li, Huajin Li, Wenting Xu, Wenting Xu, Sijia Xiang, Sijia Xiang, Leiting Tao, Leiting Tao, Wen Fu, Wen Fu, Jinhui Liu, Jinhui Liu, Wenbin Liu, Wenbin Liu, Yamei Xiao, Yamei Xiao, Liangyue Peng, Liangyue Peng   +17 more
doaj   +1 more source

Editorial: Reviews in induced pluripotent stem cells

Frontiers in Cell and Developmental Biology, 2023
No abstract ...
Mirella Dottori, Wan-Ju Li, Gabriella Minchiotti, Alessandro Rosa, Alessandro Rosa, Federica Sangiuolo   +5 more
openaire   +6 more sources

DIRECTED RE-PROGRAMMING OF SOMATIC CELLS: ADVANTAGES AND LIMITATIONS OF INDUCED PLURIPOTENT STEM CELLS (REVIEW)

Сибирский научный медицинский журнал, 2019
Stem cells are divided into embryonic and adult stem cells. The relevance of the use of stem cells in clinical practice has received new evidence in recent years however, the methods of obtaining stem cells for medical purposes cause ethical rejection ...
A. V. Korel, S. B. Kuznetsov
doaj   +1 more source

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development.

Physiological Reviews, 2019
The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same genetic code as the zygote, and that activating parts of this code are sufficient to reprogram the cell to an early developmental state.
Peter Karagiannis, Kazutoshi Takahashi, M. Saito, Y. Yoshida, K. Okita, Akira Watanabe, H. Inoue, J. Yamashita, Masaya Todani, M. Nakagawa, M. Osawa, Yoshimi Yashiro, S. Yamanaka, K. Osafune   +13 more
semanticscholar   +1 more source

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

Haematologica, 2012
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cells ...
Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay   +15 more
doaj   +1 more source

Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies

Neural Regeneration Research, 2022
Non-human primates play a key role in the preclinical validation of pluripotent stem cell-based cell replacement therapies. Pluripotent stem cells used as advanced therapy medical products boost the possibility to regenerate tissues and organs affected ...
Ignacio Rodriguez-Polo, Rüdiger Behr
doaj   +1 more source