Results 31 to 40 of about 398,685 (377)
Regenerative strategies for kidney engineering [PDF]
, 2016 The kidney is the most important organ for water homeostasis and waste excretion. It performs several important physiological functions for homeostasis: it filters the metabolic waste out of circulation, regulates body fluid balances, and acts as an ...
Garreta, Elena +2 more
core +1 more source
A village in a dish model system for population-scale hiPSC studies
Nature Communications, 2023 The mechanisms by which DNA alleles contribute to disease risk, drug response, and other human phenotypes are highly context-specific, varying across cell types and different conditions.
Drew R. Neavin +20 more
doaj +1 more source
Improving single-cell cloning workflow for gene editing in human pluripotent stem cells [PDF]
, 2018 The availability of human pluripotent stem cells (hPSCs) and progress in genome engineering technology have altered the way we approach scientific research and drug development screens.
Chen, Yi-Hsien, Pruett-Miller, Shondra M
core +2 more sources
World Journal of Stem Cells, 2021 Mesenchymal stem cells (MSCs) have received significant attention in recent years due to their large potential for cell therapy. Indeed, they secrete a wide variety of immunomodulatory factors of interest for the treatment of immune-related disorders and inflammatory diseases. MSCs can be extracted from multiple tissues of the human body.
Dupuis, Victoria +1 more
openaire +5 more sources
Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. [PDF]
PLoS ONE, 2014 In this study, we aimed to elucidate the effects and mechanism of action of valproic acid on hepatic differentiation from human induced pluripotent stem cell-derived hepatic progenitor cells.
Yuki Kondo +13 more
doaj +1 more source
International Journal of Molecular Sciences, 2018 Induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSCs) serve as a unique source for cell therapy. We investigated whether exosomes from iMSCs promote the proliferation of human keratinocytes (HaCaT) and human dermal fibroblasts (HDFs)
Soo Kim +3 more
semanticscholar +1 more source
Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy
BioResearch Open Access, 2020 The generation of induced pluripotent stem cells (iPSCs) from differentiated mature cells is one of the most promising technologies in the field of regenerative medicine.
Akram Al Abbar +4 more
semanticscholar +1 more source
Cryopreservation of Induced Pluripotent Stem Cells [PDF]
Cell Medicine, 2012 Induced pluripotent stem (iPS) cells have attracted attention as a promising cell source for medical treatment that could replace marrow stromal cells (MSCs) and adipose tissue-derived stem cells (ASCs). These pluripotent cells can be induced in vitro and in vivo to differentiate into various tissues and organs.
Hisashi Iwata +6 more
openaire +3 more sources
Human stem cells and articular cartilage regeneration. [PDF]
, 2012 The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki +2 more
core +4 more sources
Stem cell research & therapeutics, 2017 BackgroundOsteoarthritis (OA) is the most common joint disease worldwide. In the past decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA.
Yu Zhu +9 more
semanticscholar +1 more source