Results 31 to 40 of about 7,556,090 (298)

Transgene Reactivation in Induced Pluripotent Stem Cell Derivatives and Reversion to Pluripotency of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells [PDF]

Stem Cells and Development, 2016
Induced pluripotent stem cells (iPSCs) have enormous potential in regenerative medicine and disease modeling. It is now felt that clinical trials should be performed with iPSCs derived with nonintegrative constructs. Numerous studies, however, including those describing disease models, are still being published using cells derived from iPSCs generated ...
Galat, Vasiliy, Galat, Yekaterina, Perepitchka, Mariana, Jennings, Lawrence J., Iannaccone, Philip M., Hendrix, Mary J.C.   +5 more
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Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells [PDF]

, 2011
Reprogramming of adult differentiated cells to induced pluripotent stem cells (iPS) cells has been achieved by over-expression of specific transcription factors.
Maria A. Blasco, Maria A Blasco, Marión, Rosa M., Ortega Sagrario, Marión Rosa M., Schotta Gunnar, Blasco Maria A., Schotta, Gunnar, Rosa M. Marión, Blasco, Maria A., Gunnar Schotta, Sagrario Ortega, Rosa M Marión, Ortega, Sagrario   +13 more
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Organoids in domestic animals: with which stem cells?

Veterinary Research, 2021
Organoids are three-dimensional structures that are derived from the self-organization of stem cells as they differentiate in vitro. The plasticity of stem cells is one of the major criteria for generating organoids most similar to the tissue structures ...
Bertrand Pain
doaj   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G., Wobus, Anna M., Wolf, Eckhard, Prelle, Katja, Vassiliev, Ivan M.   +4 more
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Defining the Pluripotent Marker Genes for Identification of Teleost Fish Cell Pluripotency During Reprogramming

Frontiers in Genetics, 2022
Pluripotency is a transient state in early embryos, which is regulated by an interconnected network of pluripotency-related genes. The pluripotent state itself seems to be highly dynamic, which leads to significant differences in the description of ...
Huajin Li, Huajin Li, Wenting Xu, Wenting Xu, Sijia Xiang, Sijia Xiang, Leiting Tao, Leiting Tao, Wen Fu, Wen Fu, Jinhui Liu, Jinhui Liu, Wenbin Liu, Wenbin Liu, Yamei Xiao, Yamei Xiao, Liangyue Peng, Liangyue Peng   +17 more
doaj   +1 more source

DIRECTED RE-PROGRAMMING OF SOMATIC CELLS: ADVANTAGES AND LIMITATIONS OF INDUCED PLURIPOTENT STEM CELLS (REVIEW)

Сибирский научный медицинский журнал, 2019
Stem cells are divided into embryonic and adult stem cells. The relevance of the use of stem cells in clinical practice has received new evidence in recent years however, the methods of obtaining stem cells for medical purposes cause ethical rejection ...
A. V. Korel, S. B. Kuznetsov
doaj   +1 more source

A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture [PDF]

, 2012
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Lau, KX, Hughes, J., James N Hughes, Goh, HN, Joy Rathjen, Rathjen, J, Hwee Ngee Goh, Lau, K., Hughes James N., Peter D Rathjen, Rathjen Joy, Goh Hwee Ngee, Vassilieva Svetlana, Rathjen, P., Vassilieva, S., Hughes, JN, Goh, H., Familari, M., Kevin X Lau, Rathjen, J., Rathjen Peter D., Familari, M, Lau Kevin X., Mary Familari, Familari Mary, Svetlana Vassilieva, Rathjen, PD, Vassilieva, S   +27 more
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Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells [PDF]

, 2009
Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA, Bennett, DC, Patel, RH, Sviderskaya, EV, Easty, DJ, Sanchez, DP, Lawrence, MA, Anand, P, Korchev, YE   +8 more
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Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

Haematologica, 2012
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cells ...
Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay   +15 more
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Mouse induced pluripotent stem cells

The International Journal of Developmental Biology, 2008
The recent discovery that it is possible to directly reprogramme somatic cells to an embryonic stem (ES) cell-like pluripotent state, by retroviral transduction of just four genes (Oct3/4, Sox2, c-Myc and Kif4), represents a major breakthrough in stem cell research.
Geoghegan, Eamon, Byrnes, Lucy
openaire   +4 more sources