Results 41 to 50 of about 27,021 (238)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Best Sensor Configuration and Accommodation Rule Based on Navigation Performance for INS with Seven Inertial Sensors

Sensors, 2009
This paper considers the best sensor configuration and fault accommodation problem for inertial navigation systems which use seven inertial sensors such as gyroscopes and accelerometers.
Cheol-Kwan Yang, Duk-Sun Shim
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Inertial Measurement Unit Sensors in Assistive Technologies for Visually Impaired People, a Review

Sensors, 2021
A diverse array of assistive technologies have been developed to help Visually Impaired People (VIP) face many basic daily autonomy challenges.
Karla Miriam Reyes Leiva, Milagros Jaén-Vargas, Benito Codina, José Javier Serrano Olmedo   +3 more
doaj   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Upper Limb Position Tracking with a Single Inertial Sensor Using Dead Reckoning Method with Drift Correction Techniques

Sensors, 2022
Inertial sensors are widely used in human motion monitoring. Orientation and position are the two most widely used measurements for motion monitoring.
Lu Bai, Matthew G. Pepper, Zhibao Wang, Maurice D. Mulvenna, Raymond R. Bond, Dewar Finlay, Huiru Zheng   +6 more
doaj   +1 more source

On the Impact Energy Absorption of an Advanced High‐Strength Bilayer Steel Composite Consisting of Carbide‐Free Bainitic Steel and High‐Mn Twinning‐Induced Plasticity Steel

Advanced Engineering Materials, EarlyView.
Excellent combinations of strength and impact toughness are obtained in a bilayer composite of high‐strength carbide‐free bainitic (CFB) steel and high‐ductility twinning‐induced plasticity (TWIP) steel. The composite absorbs energy at small strains when the notch is placed on the TWIP side and at high strains when the notch is placed on the CFB side ...
Kendra Hawke, Xiaogang Li, Amir Partovi, Colin Scott, Fateh Fazeli, Hatem Zurob   +5 more
wiley   +1 more source

Hybrid Auxetic Architectures: Integrating Curvature‐Driven Design for Enhanced Mechanical Tunability and Structural Performance

Advanced Engineering Materials, EarlyView.
Curvature‐tuned auxetic lattices are designed, fabricated, and mechanically characterized to reveal how geometric curvature governs stretchability, stress redistribution, and Poisson's ratio evolution. Photoelastic experiments visualize stress pathways, while hyperelastic simulations quantify deformation mechanics.
Shuvodeep De, Giovanni Meli, Meysam Khaleghian, Anahita Emami   +3 more
wiley   +1 more source

Experimental Verification of Inertial Navigation with MEMS for Forensic Investigation of Vehicle Collision [PDF]

Radioengineering, 2016
This paper studies whether low-grade inertial sensors can be adequate source of data for the accident characterization and the estimation of vehicle trajectory near crash.
S. Tadic, M.B. Vukajlovic
doaj