Results 31 to 40 of about 834,111 (218)
International Journal of Infectious Diseases, 2021 Botulism, a rare life-threatening toxemia, is probably underdiagnosed in all of its forms in Africa. This study reports the first laboratory-supported case of infant botulism on the African continent.
Marné N. Vosloo +10 more
doaj +1 more source
Journal of Perinatology, 2007 Infant botulism results from the absorption of heat-labile neurotoxin produced in situ by ingested Clostridium botulinum. Honey and environmental exposure are the main sources of acquisition of the organism. Clinical manifestations are owing to progressive neuromuscular blockade, initially of muscles innervated by cranial nerves and later of the trunk,
+5 more sources
Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review. [PDF]
J NeurochemBotulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Monash A, Tam J, Rosen O, Soreq H.
europepmc +2 more sources
The First Reported Case of Infant Botulism in Korea: Treatable Infantile Neuromuscular Disease. [PDF]
J Korean Med Sci, 2020 Botulism is a rare neuromuscular disorder caused by neurotoxins produced by Clostridium botulinum. The diagnosis of infant botulism may be obscured or delayed, as its presentation is similar to that of infantile neuromuscular disorders.
Jang HG, Jang J, Jung HJ, Jung DE.
europepmc +2 more sources
Archivos de pediatria, 2023 nfant botulism is the most common form of human botulism in the United States. Most cases are caused by toxin types A and B, which are treated with Human Botulism Immune Globulin Intravenous (BIG-IV; BabyBIG ® ).
D. Primdahl +8 more
semanticscholar +1 more source
Emergency Care Journal, 2008 Infant Botulism is a form of human botulism in which ingested spores of Clostridium botulinum germinate, colonize the infant’s colon, in which they produce botulinum neurotoxin.
Davide Lonati +8 more
doaj +1 more source
A case of infant botulism in a 4-month-old baby [PDF]
, 2016 This case-report highlights: i) the difficulty of IB diagnosis as it is a rare syndrome with subclinical onset, ii) the need for an accurate training for physicians involved in IB management, iii) the efficacy and safety of TEqA in IB treatment, iv ...
Bruna Auricchio +6 more
core +1 more source
Exploring the genetic background of the botulism neurotoxin BoNT/B2 in Spain
Microbiology Spectrum, 2023 To determine whether the neurotoxin BoNT/B2 causing botulism in Spain is clonal, the genetic diversity and phylogenetic relationships of Clostridium botulinum from food-borne episodes and infant cases of the condition were explored.
Sylvia Valdezate +7 more
doaj +1 more source
Denmark: Botulism in an infant or infant botulism? [PDF]
Eurosurveillance, 2008 A 4.5 months old, previously healthy Danish girl was admitted to a paediatric department after six days of passive behaviour and weak suck. Over the next days she became increasingly weak, developed bilateral ptosis, the muscle stretch reflexes were lost, and mydriasis with slow pupillary responses was noted.
A, Paerregaard +5 more
openaire +2 more sources
Infant botulism: a descriptive study in a pediatric intensive care unit.
Archivos Argentinos de Pediatria, 2022 Introduction. Infant botulism (IB) is the most common form of human botulism in Argentina. Our objective was to describe the main aspects of diagnosis and management of patients with IB admitted to the pediatric intensive care unit (PICU).
Carla E Ávila +4 more
semanticscholar +1 more source