Results 41 to 50 of about 157,115 (258)
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Safety vs. Sustainability Concerns of Infant Food Users: French Results and European Perspectives
, 2021 International audienceContext. In line with Sustainable Development Goals 3 “Good health and well-being” and 12 “Responsible Consumption and Production”, this paper is concerned with the fragile population of the less-than-3-years-old children.
Rallou Thomopoulos +3 more
core +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
, 1993 copyright UK Data Service and data collection copyright owner.The Infant Feeding Survey (IFS) has been carried out every five years since 1975, in order to establish information about infant feeding practices.
Office of Population Censuses and Surveys, Social Survey Division
core +1 more source
Advanced Science, EarlyView.Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
, 1993 copyright UK Data Service and data collection copyright owner.The Infant Feeding Survey (IFS) has been carried out every five years since 1975, in order to establish information about infant feeding practices.
Office of Population Censuses and Surveys, Social Survey Division
core +1 more source
Advanced Science, EarlyView.Herein, we propose a solar‐powered heavy metal trap (SPHT) for sludge disposal. The indoor experiments demonstrated that the sludge water content decreased from 90 % to 31 %, coupled with a decrease in heavy metal content to 6 % at most. Furthermore, the designed SPHT generated an initial potential of 0.10 V, and monitoring this hydrovoltaic potential ...
Yanlin Li +7 more
wiley +1 more source
Infant welfare, philanthropy and entrepreneurship in Glasgow: Sister Laura’s Infant Food Company
, 2008 Laura Smith was sister-in-charge of the Children’s Dispensary in Glasgow from 1897 to 1922. In 1911 she established Sister Laura’s Infant Food Company to market a special milk formula of her own invention. The directors of the Dispensary were not amused.
Weaver, L.T., Gemmell, S.
core
Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes [PDF]
, 2009 Background: The Cronobacter genus (Enterobacter sakazakii) has come to prominence due to its association with infant infections, and the ingestion of contaminated reconstituted infant formula. C. sakazakii and C.
Loughlin, Michael, Dr. +20 more
core +1 more source
Advanced Science, EarlyView.Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An +11 more
wiley +1 more source