Results 111 to 120 of about 172,040 (288)

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

Advanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis, Joanne Heade, Cristiana Cunha, Marco van de Weert, Lasse Saaby, Stine Rønholt, Hanne Mørck Nielsen   +6 more
wiley   +1 more source

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

Advanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim, Inhyuk Hwang, Juhee Seo, Chaiwon Kim, In‐Jeong Choi, Miran Kang, Min‐Seok Rha, Youngjae Hong, Jooyoung Kim, Seung‐Ki Baek, Jung‐Hwan Park, Hyung‐Ju Cho, Kihyuck Kwak   +12 more
wiley   +1 more source

Some of the Factors Involved in Male Infertility: A Prospective Review

International Journal of General Medicine, 2020
Emad Babakhanzadeh,1,2 Majid Nazari,1 Sina Ghasemifar,1 Ali Khodadadian1 1Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 2Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical ...
Babakhanzadeh E, Nazari M, Ghasemifar S, Khodadadian A   +3 more
doaj  

Mesoporous Fe3O4 Nanoparticles Loaded with IR‐820 for Antibacterial Activity via Magnetic Hyperthermia Combined with Photodynamic Therapy

Advanced Healthcare Materials, EarlyView.
This study addresses bacterial biofilm resistance by developing mesoporous Fe3O4 nanoparticles loaded with photosensitizer IR‐820, enabling combined antimicrobial photodynamic therapyand magnetic hyperthermia therapy. The system achieves magnetic targeting, heat‐triggered drug release under alternating magnetic fields, and near‐infrared‐induced ROS ...
Yuange Li, Song Xue, Hong Sung Min, Chen Chen, Liheng Lu, Zhiheng Chen, Haojie Shan, Fuli Yin, Xiaowei Yu   +8 more
wiley   +1 more source

954 Clinical results from a phase I dose escalation study in treatment-naïve early stage prostate cancer patients with ORCA-010, a potency enhanced oncolytic replication competent adenovirus

Journal for ImmunoTherapy of Cancer, 2021
Richard Casey, Wenliang Dong, Tereza Brachtlova, Allan Abramovitch, Jonathan Giddens, Peter Incze, Kenneth Jansz, Victor van Beusechem   +7 more
doaj   +1 more source

L'infertilité mâle aujourd'hui. [Male infertility today].

, 2012
International audienceAu siècle dernier, plus exactement en avril 1995, la revue médecine/sciences consacrait pour la première fois un de ses numéros au testicule.
Jégou, Bernard
core   +3 more sources

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Male infertility. [PDF]

BMJ, 1972
openaire   +3 more sources

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back, Moonkyoung Jeong, Huyen‐Thao Le, Ji‐Ho Park   +3 more
wiley   +1 more source

The prevalence of infertility and related factors in patients referred to infertility center in Besat hospital, Sanandaj, Iran

Chronic Diseases Journal, 2019
BACKGROUND: Infertility is considered as a prominent health care issue. The present study aimed to determine the prevalence rate of infertility and certain factors relevant to it.
Sholeh Shagheibi, Fariba Seyedoshohadaie, Ghobad Moradi, Azim Gholami, Samaneh Rouhi   +4 more
doaj