Results 201 to 210 of about 197,632 (380)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Inflammatory osteolysis: A conspiracy against bone [PDF]

, 2017
Abu-Amer, Abu-Amer, Anton, Bardin, Beranger, Chen, Christo, Claro, Cobelli, Coll, Dapunt, Deborah V. Novack, Dewhirst, Gabriel Mbalaviele, Georg Schett, Gravallese, Harre, Josse, Jovanovic, Kollias, Lukens, Maitra, McCall, Mukai, Negishi-Koga, Osta, Ozen, Pasco, Robaszkiewicz, Rubbert-Roth, Sanchez, Scianaro, Sharma, Steven L. Teitelbaum, Van Hauwermeiren, Wang, Zaki   +36 more
core   +2 more sources

SnapShot: Inflammasomes

Cell, 2013
Atianand, Maninjay K., Rathinam, Vijay A. K., Fitzgerald, Katherine A   +2 more
openaire   +3 more sources

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

Advanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Wang, Gang Chen   +10 more
wiley   +1 more source

Mechanism and Regulation of NLRP3 Inflammasome Activation.

TIBS -Trends in Biochemical Sciences. Regular ed, 2016
Yuan He, H. Hara, G. Núñez
semanticscholar   +1 more source

Body Mass Index as a Potential Mediator of the Association Between Gout and Hypertension Among Chinese Older Adults: A Mediation Analysis in a Cross‐Sectional Study

AGING MEDICINE, EarlyView.
This study employed mediation analysis and found that BMI played a significant mediating role in the relationship between gout and hypertension. The mediating effect accounted for 12.59% of the total effect (ACME = 0.0244). ACME, average causal mediation effect.
Jia Wang, Jian‐bo Zhan, Lei Yi, Can Mei, Lin‐wanyue Chen, Gui‐ping Wang, Zi‐jun Shi, Wei‐ji Zhou, Chang‐e Xiong, Jing Cheng   +9 more
wiley   +1 more source

Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages

, 2007
Yan Qu, Luigi Franchi, Gabriel Núñez, George Dubyak   +3 more
openalex   +1 more source

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans [PDF]

, 2009
Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan, Krupen Patel, Brian A. Hall, Gordon D. Brown, Katherine A. Fitzgerald   +6 more
openalex   +1 more source

Cryopyrin activates the inflammasome in response to toxins and ATP

Nature, 2006
S. Mariathasan, D. Weiss, K. Newton, J. McBride, K. O’Rourke, M. Roose-Girma, Wyne P. Lee, Y. Weinrauch, D. Monack, V. Dixit   +9 more
semanticscholar   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source