NEK7 Cys298 is important for NLRP3 inflammasome and targetable by dimethyl fumarate. [PDF]
Cell Chem BiolZhang Y +11 more
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
iNew Medicine, EarlyView.ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Time-lapse image analysis reveals trigger-dependent differences in ASC speck lifetime in the NLRP3 inflammasome. [PDF]
Sci RepHerring M +7 more
europepmc +1 more source
Molecular mechanisms of NLRP3 inflammasome activation. [PDF]
Exp Mol MedShin HJ, Kim IS, Kim JK, Jo EK.
europepmc +1 more source
Convergent death programs in chronic obstructive pulmonary disease: how pyroptotic and ferroptotic crosstalk reshapes therapeutic paradigms. [PDF]
Front ImmunolHuang A, Liu S, Lan J.
europepmc +1 more source
Human umbilical cord mesenchymal stem cell-derived exosomes are associated with changes in renal injury markers, gut microbiota composition, and inflammatory signaling in IgA nephropathy. [PDF]
Front ImmunolHe Y +6 more
europepmc +1 more source
High-Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor. [PDF]
MedComm (2020)Ji SL +11 more
europepmc +1 more source
Correction to "MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression". [PDF]
Anesthesiol Res Practeuropepmc +1 more source