Results 231 to 240 of about 163,829 (303)

NLRP3 Inflammasome Activation Mediates Coronary Artery Lesions in Kawasaki Disease by Inducing Endothelial Cells Pyroptosis and Glycocalyx Injury. [PDF]

Immun Inflamm Dis
Zheng R, Yue J, Chen Q, Xie J, Wen L, Duan N, Shang J, Zhu S, Huang L, Zou Y, Song X, Wu X, Feng Q.   +12 more
europepmc   +1 more source

Association between serum α‐Klotho levels and severity of periodontitis in a representative U.S. population

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α‐Klotho, an anti‐aging protein with anti‐inflammatory properties, has been associated with systemic diseases, but its role in periodontitis is unclear.
Hamoun Sabri, Sahar Baniameri, Pranav Kataria, Hend Abulatifa, Parham Hazrati, Hom‐Lay Wang, Muhammad H. A. Saleh   +6 more
wiley   +1 more source

The cardiovascular-immune axis: crosstalk and therapy in atherosclerosis, myocarditis and vasculitis. [PDF]

Front Immunol
Liao YP, Wei YX, Zhang FM, Zhang ZS, Xu SP, You YH, Guo JW.   +6 more
europepmc   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Human resistin is critical to activation of the NLRP3 inflammasome in macrophages. [PDF]

PLoS One
Kariyawasam U, Lam W, Skinner J, Chakrabarti R, Cox A, Hassoun PM, Lin Q, Johns RA.   +7 more
europepmc   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

Complement, Inflammasome, and Microglial Crosstalk in Glaucoma: From Neurodegeneration to Immune-Based Precision Therapy. [PDF]

Life (Basel)
Chen TY, Wu N, Sun X.
europepmc   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Ion channels and GPCRs as pharmacological regulators of ferroptosis and pyroptosis in metabolic diseases. [PDF]

Diabetol Metab Syndr
Nurkolis F.
europepmc   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source