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Antiviral Inflammasomes and How to Find Them. [PDF]
VirusesWuerth JD, Schmidt FI.
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Mitochondrial Dysfunction in the Inflammatory Process of Neurodegenerative Diseases. [PDF]
BiomedicinesNesci S.
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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review). [PDF]
Mol Med RepLi Z +6 more
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Immunometabolic Regulation of Neuroinflammation in Retinitis Pigmentosa: Roles of Microglia, Müller Glia, and Regulated Cell Death. [PDF]
BiomoleculesYang Y, Zhou P, Deng Y, Peng Q.
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The ASC-c isoform as a modulator of inflammasome activation: Insights into molecular mechanisms and therapeutic applications. [PDF]
J Biol ChemSharma M +6 more
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Molecular Aspects of Medicine, 2020
NOD-like receptor family pyrin domain containing 6 (NLRP6) is a novel NLR family member, that shows high expression in the intestine and liver (in contrast to NLRP3 in myeloid cells), to regulate inflammation and host defense against microbes. NLRP6 is reported to involved in inflammasome activation, regulation of nuclear factor-κB (NF-κB) and mitogen ...
Runzhi, Li, Shu, Zhu
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NOD-like receptor family pyrin domain containing 6 (NLRP6) is a novel NLR family member, that shows high expression in the intestine and liver (in contrast to NLRP3 in myeloid cells), to regulate inflammation and host defense against microbes. NLRP6 is reported to involved in inflammasome activation, regulation of nuclear factor-κB (NF-κB) and mitogen ...
Runzhi, Li, Shu, Zhu
openaire +2 more sources
2023
The innate immune response represents the first line of host defense, and it is able to detect pathogen- and damage-associated molecular patterns (PAMPs and DAMPs, respectively) through a variety of pattern recognition receptors (PRRs). Among these PRRs, certain cytosolic receptors of the NLRs family (specifically NLRP1, NLRP3, NLRC4, and NAIP) or ...
Vinicius Nunes Cordeiro, Leal +1 more
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The innate immune response represents the first line of host defense, and it is able to detect pathogen- and damage-associated molecular patterns (PAMPs and DAMPs, respectively) through a variety of pattern recognition receptors (PRRs). Among these PRRs, certain cytosolic receptors of the NLRs family (specifically NLRP1, NLRP3, NLRC4, and NAIP) or ...
Vinicius Nunes Cordeiro, Leal +1 more
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2016
Pattern recognition receptors, including members of the NLR and PYHIN families, are essential for recognition of both pathogen- and host-derived danger signals. A number of molecules in these families are capable of forming multiprotein complexes termed inflammasomes that result in the activation of caspase-1.
Ann M, Janowski, Fayyaz S, Sutterwala
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Pattern recognition receptors, including members of the NLR and PYHIN families, are essential for recognition of both pathogen- and host-derived danger signals. A number of molecules in these families are capable of forming multiprotein complexes termed inflammasomes that result in the activation of caspase-1.
Ann M, Janowski, Fayyaz S, Sutterwala
openaire +2 more sources