Results 191 to 200 of about 163,829 (303)

Pulmonary Vascular Signaling in Pulmonary Hypertension: Potential Role of Endothelial Ca²⁺ Signaling in Cellular Senescence and Inflammasome Activation. [PDF]

Arterioscler Thromb Vasc Biol
Wang WT, Li X, Wang T, Ferrizzi SA, Avchalumov Y, Thistlethwaite PA, Makino A, Yuan JX.   +7 more
europepmc   +1 more source

["The inflammasomes"].

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2012
Inflammation is a host adaptational response to cell injury caused by various exogenous and endogenous stimuli. IL-1β, which is an important proinflammatory cytokine secreted at the site of cellular injury, plays an important role in inflammation. Inflammasome is an intracellular multi-protein complex that mediates caspase-1-dependent processing of IL ...
openaire   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy. [PDF]

Immun Inflamm Dis
Zhao S, Li Y, Li W, Dong L, Lian R, Luo Q, Lian X, Li J, He F.   +8 more
europepmc   +1 more source

Metformin Inhibits Inflammation by Targeting the NLRP3 Inflammasome: Linking NF-κB/NEK7/AMPK Signaling to Mitochondrial Function. [PDF]

J Inflamm Res
Ning D, Jiang C, Zeng J, Zeng F, Zheng X, Xia P, Liu Y, Huang X, Zhang D, Liu X, Zhang J, Yu P.   +11 more
europepmc   +1 more source

The Open Reading Frame 7b of the SARS-CoV-2 Disperse Trans-Golgi and Activate the NLRP3 Inflammasome. [PDF]

J Med Virol
García-Villalba J, Hurtado-Navarro L, Angosto-Bazarra D, Baroja-Mazo A, Pelegrin P.   +4 more
europepmc   +1 more source

IFI204-STING drives protective innate immunity against gangrenous <i>Clostridium perfringens</i> infection via regulation of NLRP3 signaling. [PDF]

Front Immunol
Zhang MY, Li JQ, Xu Q, Zhuang ZJ, Liang J, He AB, Zhang SX, Zhao Y, Chen X, Li ZY, Sheng P, Liu Y, Yu SX.   +12 more
europepmc   +1 more source

Cofilin-1 is a redox-sensitive guard of the NLRP3 inflammasome. [PDF]

Nat Immunol
Park YH, Batu ED, Matthiasardottir B, Kim Y, Akkaya-Ulum YZ, Kastner DL, Chae JJ.   +6 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Editorial Note: Tilianin attenuates inflammasome activation in endothelial progenitor cells to mitigate myocardial ischemia-reperfusion injury. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source