Results 241 to 250 of about 197,632 (380)

Serum cytokine profiling differentiates underlying diseases in cytokine storm syndrome

Arthritis &Rheumatology, Accepted Article.
Objective Cytokine storm syndrome (CSS), commonly associated with hemophagocytic lymphohistiocytosis (HLH), is a fatal hyperinflammatory syndrome. Differentiating the underlying diseases responsible for CSS is essential for timely therapeutic decisions. This study explored the clinical usefulness of serum cytokine profiling in distinguishing underlying
Shuya Kaneko, Maho Hatano, Asami Shimbo, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mao Mizuta, Yasuo Nakagishi, Keiji Akamine, Naomi Iwata, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Koji Yokoyama, Toshinori Minato, Kazushi Izawa, Takahiro Yasumi, Tadashi Matsubayashi, Tadashi Hosoya, Hiroki Nishikawa, Junya Fujimura, Ryoko Asano, Yuko Sugita, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhide Eguchi, Ryuta Nishikomori, Ryuhei Yasuoka, Takaki Asano, Miyako Kanno, Kazuya Hamada, Yuji Fujita, Daisuke Hayashi, Shojiro Watanabe, Takeshi Shiba, Shinsuke Yasuda, Masaaki Mori, Hirokazu Kanegane, Masatoshi Takagi, Masaki Shimizu   +42 more
wiley   +1 more source

Inflammasome activation and accelerated immune aging in autoimmune disorders. [PDF]

Front Aging
Mittal R, Saavedra D, Mittal M, Lemos JRN, Hirani K.   +4 more
europepmc   +1 more source

Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases

, 2009
Marina Tiemi Shio, Stephanie C. Eisenbarth, Myriam Savaria, Adrien F. Vinet, Marie-Josée Bellemare, Kenneth W. Harder, Fayyaz S. Sutterwala, D. Scott Bohle, Albert Descoteaux, Richard A. Flavell, Martin Olivier   +10 more
openalex   +2 more sources

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome [PDF]

, 2010
Christian Bauer, Peter Duewell, Christine Mayer, Hans A. Lehr, Katherine A. Fitzgerald, M Dauer, J Tschopp, Stefan Endres, Eicke Latz, Max Schnurr   +9 more
openalex   +1 more source

TIM-3 restrains anti-tumour immunity by regulating inflammasome activation

Nature, 2021
Karen O. Dixon, M. Tabaka, M. Schramm, S. Xiao, Ruihan Tang, Danielle Dionne, A. Anderson, O. Rozenblatt-Rosen, A. Regev, V. Kuchroo   +9 more
semanticscholar   +1 more source

Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients

Arthritis &Rheumatology, Accepted Article.
Objectives Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis.
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

Transformation of acute kidney injury to chronic kidney disease: the interaction between mitophagy and NLRP3 inflammasome. [PDF]

Front Mol Biosci
Zhu Y, Lv C, Qiao Y, Yang H, Lin W, Wang X, Zhang Y, Yang B.   +7 more
europepmc   +1 more source

Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular Pathogen Chlamydia trachomatis

, 2009
Ali A. Abdul‐Sater, Evonne Koo, Georg Häcker, David M. Ojcius   +3 more
openalex   +1 more source

Spermidine reproduces the anti‐inflammatory effects of intermittent fasting and prevents urate and calcium pyrophosphate crystal‐induced inflammation

Arthritis &Rheumatology, Accepted Article.
Background Gout due to the formation of monosodium urate (MSU) crystals and calcium pyrophosphate (CPP) deposition disease are two major types of microcrystalline pathologies in adults. They are responsible for recurrent flares that rely on interleukin (IL)‐1β via activation of the NLRP3 inflammasome.
Chinh Nghia Pham, Florence Castelli, Flora Finet, Charles Leroy, Céline Chollet, Twinu Wilson Chirayath, Subhalaxmi Moitra, Mylène Zarka, Agnès Ostertag, François Brial, Christèle Combes, Augustin Latourte, Thomas Bardin, François Fenaille, Pascal Richette, Hang Korng Ea   +15 more
wiley   +1 more source

M464 inhibits activation of NLRP3 inflammasome and inflammatory response in mice. [PDF]

Sci Rep
Wang W, Zhao Y, Li S, Wu T, Hu K, Liu W, Cheng C, Fu X, Xu G.   +8 more
europepmc   +1 more source