Results 271 to 280 of about 197,632 (380)

Regulatory Mechanism and Drug Therapy of NLRP3 Inflammasome in Recurrent Pregnancy Loss: Research Status and Prospect. [PDF]

J Inflamm Res
Cui Y, Yang Y, Li Y, Zhang Y, Niu D, Feng X.   +5 more
europepmc   +1 more source

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

, 2009
Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Pétrilli, Carmen Gómez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Estéban, Thierry Calandra   +12 more
openalex   +2 more sources

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion [PDF]

, 2010
Takahiro Shimada, Bong Goo Park, Andrea J. Wolf, Constantinos Brikos, Helen S. Goodridge, Courtney Becker, Christopher N. Reyes, Edward A. Miao, Alan Aderem, Friedrich Götz, George Y. Liu, David M. Underhill   +11 more
openalex   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Macrophage NLRP3 activation and IL-1β release drive osimertinib-induced antitumor immunity. [PDF]

J Immunother Cancer
Yu H, Sun X, Li Y, Pan J, Liu X, He H, Wu H, Sun Y, Pan Y, Qian X.   +9 more
europepmc   +1 more source

Inflammasomes as mediators of immunity against influenza virus [PDF]

, 2010
Iris K. Pang, Akiko Iwasaki
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Pyroptosis in Respiratory Virus Infections: A Narrative Review of Mechanisms, Pathophysiology, and Potential Therapeutic Interventions. [PDF]

Microorganisms
Lin R, Porto BN.
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats. [PDF]

J Inflamm Res
Wu Z, Fang Y, Dong Y, Qin Y, Liu A, Han T, Song P, Shen C.   +7 more
europepmc   +1 more source