Results 271 to 280 of about 190,243 (379)

Inflammasomes and Signaling Pathways: Key Mechanisms in the Pathophysiology of Sepsis. [PDF]

Cells
Saavedra-Torres JS, Pinzón-Fernández MV, Ocampo-Posada M, Nati-Castillo HA, Jiménez Hincapie LA, Cadrazo-Gil EJ, Arias-Intriago M, Rojas-Cadena M, Tello-De-la-Torre A, Osejos W, Izquierdo-Condoy JS.   +10 more
europepmc   +1 more source

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

, 2009
Kate Schroder, Daniel A. Muruve, Jürg Tschopp   +2 more
openalex   +1 more source

Inflammation and Fibrosis duringChlamydia pneumoniaeInfection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome [PDF]

, 2010
Xianbao He, Samrawit Mekasha, Nikolaos Mavrogiorgos, Katherine A. Fitzgerald, Egil Lien, Robin R. Ingalls   +5 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular Pathogen Chlamydia trachomatis

, 2009
Ali A. Abdul‐Sater, Evonne Koo, Georg Häcker, David M. Ojcius   +3 more
openalex   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer's disease associated with inflammasome activation and ASC speck propagation. [PDF]

J Neuroinflammation
Brezani V, Joshi RS, Ortega-Ribera M, Nagesh PT, Brezani V, Zivny A, Kurt-Jones EA, Golenbock DT, Szabo G.   +8 more
europepmc   +1 more source

Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals [PDF]

, 2010
Peter Duewell, Hajime Kono, Katey J. Rayner, Cherilyn M. Sirois, Gregory I. Vladimer, Franz Bauernfeind, George S. Abela, Luigi Franchi, Gabriel Núñez, Max Schnurr, Terje Espevik, Egil Lien, Katherine A. Fitzgerald, Kenneth L. Rock, Kathryn J. Moore, Samuel D. Wright, Veit Hornung, Eicke Latz   +17 more
openalex   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1485-1489, April 2025.
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Sanjay Divakaran, Vinay Randhawa, Usman A. Tahir, Matthew Robertson, Anam A. Waheed, Anna Perillo, Leanne Barrett, Ron Blankstein, Mark W. Feinberg, Marcelo F. Di Carli, Neal K. Lakdawala   +10 more
wiley   +1 more source