Results 11 to 20 of about 156,509 (154)
Genomic instability in chronic airway inflammatory diseases
Biomedical Journal, 2015 Chronic airway inflammatory diseases are life-threatening conditions, including bronchial asthma, chronic obstructive pulmonary disease (COPD), and so on.
Zhengqiang Bao +5 more
doaj +3 more sources
Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease. [PDF]
Int J Mol Sci, 2022 In the lung, glycosaminoglycans (GAGs) are dispersed in the extracellular matrix (ECM) occupying the interstitial space between the capillary endothelium and the alveolar epithelium, in the sub-epithelial tissue and in airway secretions. In addition to playing key structural roles, GAGs contribute to a number of physiologic processes ranging from cell ...
Caird R +6 more
europepmc +4 more sources
Niclosamide repurposed for the treatment of inflammatory airway disease. [PDF]
JCI Insight, 2019 Inflammatory airway diseases, such as asthma, cystic fibrosis (CF), and chronic obstructive pulmonary disease (COPD), are characterized by mucus hypersecretion and airway plugging. In both CF and asthma, enhanced expression of the Ca 2+ -activated Cl ...
Cabrita I +3 more
europepmc +4 more sources
Frontiers in Medicine, 2020 Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath.
Kenneth P. Hough +6 more
doaj +1 more source
Regulatory T cells mediated immunomodulation during asthma: a therapeutic standpoint
Journal of Translational Medicine, 2020 Asthma is an inflammatory disease of the lung airway network, which is initiated and perpetuated by allergen-specific CD4+ T cells, IgE antibodies, and a massive release of Th2 cytokines.
Mohammad Afzal Khan
doaj +1 more source
Frontiers in Microbiology, 2013 Asthma is a serious health and socioeconomic issue all over the world, affecting more than 300 million individuals. The disease is considered as an inflammatory disease in the airway, leading to airway hyperresponsiveness, obstruction, mucus hyper ...
Makoto eKudo +2 more
doaj +1 more source
The Novel Regulatory Role of the lncRNA–miRNA–mRNA Axis in Chronic Inflammatory Airway Diseases
Frontiers in Molecular Biosciences, 2022 Chronic inflammatory airway diseases, characterized by airway inflammation and airway remodelling, are increasing as a cause of morbidity and mortality for all age groups and races across the world. The underlying molecular mechanisms involved in chronic
Xin Qiao +9 more
doaj +1 more source
Frontiers in Microbiology, 2017 The respiratory tract is a complex system that is inhabited by niche-specific communities of microbes including bacteria, fungi, and viruses. These complex microbial assemblages are in constant contact with the mucosal immune system and play a critical ...
Irene Zhang +4 more
doaj +1 more source
Inflammatory bowel disease and airway diseases
World Journal of Gastroenterology, 2016 Airway diseases are the most commonly described lung manifestations of inflammatory bowel disease (IBD). However, the similarities in disease pathogenesis and the sharing of important environmental risk factors and genetic susceptibility suggest that there is a complex interplay between IBD and airway diseases.
Vutcovici, Maria +2 more
openaire +2 more sources
Prevalence of inflammatory bowel disease in patients with airways disease [PDF]
Respiratory Medicine, 2008 Case reports and case series have suggested an association between inflammatory bowel disease (IBD) and airways disease, but there are no data demonstrating a higher prevalence of IBD among patients with airways disease. Furthermore, no consistent radiological, pulmonary or pathological abnormalities have been demonstrated in patients with both ...
Raj, A +5 more
openaire +3 more sources