Results 31 to 40 of about 1,145,138 (308)

Cytokine profile in childhood asthma

Journal of Medical Science, 2022
Childhood asthma is a chronic airway disease, which pathogenesis is markedly heterogeneous–with multiple phenotypes defining visible characteristics and endotypes defining molecular mechanisms.
Joanna Matysiak, Kacper Packi, Sylwia Klimczak, Patrycja Bukowska, Eliza Matuszewska, Agnieszka Klupczyńska-Gabryszak, Anna Bręborowicz, Jan Matysiak   +7 more
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Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation [PDF]

International Journal of Molecular Sciences, 2019
A key role of the mitochondrial Translocator Protein 18 KDa (TSPO) in neuroinflammation has been recently proposed. However, little is known about TSPO-activated pathways underlying the modulation of reactive microglia. In the present work, the TSPO activation was explored in an in vitro human primary microglia model (immortalized C20 cells) under ...
Eleonora Da Pozzo, Chiara Tremolanti, Barbara Costa, Chiara Giacomelli, Vladimir M. Milenkovic, Stefanie Bader, Christian H. Wetzel, Rainer Rupprecht, Sabrina Taliani, Federico Da Settimo, Claudia Martini   +10 more
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The prognostic capability of inflammatory proteins in predicting peripheral artery disease related adverse events

Frontiers in Cardiovascular Medicine, 2022
BackgroundLevels of inflammatory proteins and their prognostic potential have been inadequately studied in patients with peripheral artery disease (PAD).
Ben Li, Niousha Djahanpour, Abdelrahman Zamzam, Muzammil H. Syed, Shubha Jain, Sara Arfan, Rawand Abdin, Mohammad Qadura, Mohammad Qadura, Mohammad Qadura   +9 more
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The allograft inflammatory factor‐1 family of proteins [PDF]

FEBS Letters, 2002
The allograft inflammatory factor‐1 (AIF‐1) is a 17 kDa interferon‐γ‐inducible Ca2+‐binding EF‐hand protein that is encoded within the HLA class III genomic region. Three proteins are probably identical with AIF‐1 termed Iba1 (ionized Ca2+‐binding adapter), MRF‐1 (microglia response factor) and daintain.
Deininger, Martin H, Meyermann, Richard, Schluesener, Hermann J   +2 more
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Acute paretic syndrome in juvenile White Leghorn chickens resembles late stages of acute inflammatory demyelinating polyneuropathies in humans [PDF]

, 2010
Background: Sudden limb paresis is a common problem in White Leghorn flocks, affecting about 1% of the chicken population before achievement of sexual maturity.
Sascha Trapp, Bader, Sophie R., Hans-Christian Philipp, Kaspers, Bernd, Bader, Sophie R, Steffen Weigend, Sharifi, Ahmad R, Philipp, Hans-Christian, Trapp, Sascha, Sonja Kothlow, Weigend, Steffen, Sharifi, Ahmad R., Matiasek, Kaspar, Susanne CN Schwarz, Schmahl, Wolfgang W., Bernd Kaspers, Schwarz, Susanne C.N., Kothlow, Sonja, Sharifi, Ahmad Reza, Schwarz, Susanne C. N., Preisinger, Rudolf, Ahmad R Sharifi, Wolfgang Schmahl, Sophie R Bader, Kaspar Matiasek, Schmahl, Wolfgang, Rudolf Preisinger   +26 more
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Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]

, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Anderson, George, Leonard, B, Cai Song, Goehler, Lisa, Gałecki, Piotr, Michael Berk, Michael Maes, Berk, M, Berk, Michael, Maes, Michael, Song, Cai, Leonard, B., Anderson, G, Anderson, G., Leonard, Brian, Maes, M., Piotr Gałecki, Goehler, L., Gałecki, P., Berk, M., Goehler, L, Brian Leonard, Song, C, Gałecki, P, Lisa Goehler, George Anderson, Maes, M, Song, C.   +27 more
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Inflammatory proteins: Chemical and biological aspects [PDF]

Clinical Biochemistry, 1980
Mediators of the inflammatory system can be broadly described as those that pre-exist and are released by active secretory mechanisms from storage granules (as in the case of vasoactive amines within cytoplasmic granules of mast cell), those that are biosynthetically generated de novo (as in the case of prostaglandins) and those that are produced by ...
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Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [PDF]

, 2013
Objective: Inhibitor of apoptosis proteins (IAPs), such as X-linked or cellular IAP 1/2 (XIAP, cIAP1/2), are important regulators of apoptosis. IAP antagonists are currently under clinical investigation as anticancer agents.
Mayer, Bettina A., Kracht, Michael, Rehberg, Markus, Reichel, Christoph A., Vollmar, Angelika M., Tiegs, Gisa, Wolf, Alexander, Krombach, Fritz, Zahler, Stefan, Fürst, Robert, Erhardt, Annette   +10 more
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The detection of surfactant proteins A, B, C and D in the human brain and their regulation in cerebral infarction, autoimmune conditions and infections of the CNS [PDF]

, 2013
Surfactant proteins (SP) have been studied intensively in the respiratory system. Surfactant protein A and surfactant protein D are proteins belonging to the family of collectins each playing a major role in the innate immune system.
Dankwart Stiller, Stefan Schob, Lars Bräuer, Kekulé, Alexander, Alexander S Kekulé, Erik Maronde, Maronde, Erik, Bräuer, Lars, Stiller, Dankwart, Sel, Saadettin, Schicht, Martin, Saadettin Sel, Alexander S. Kekulé, Martin Schicht, Schob, Stefan, Paulsen, Friedrich, Friedrich Paulsen   +16 more
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Exploration of the causal associations between circulating inflammatory proteins, immune cells, and neuromyelitis optica spectrum disorder: a bidirectional Mendelian randomization study and mediation analysis

Frontiers in Aging Neuroscience
BackgroundAn increasing body of research has demonstrated a robust correlation between circulating inflammatory proteins and neuromyelitis optica spectrum disorders (NMOSD).
Zhiqing Chen, Yujin Guo, Huaiyu Sun, Wuqiong Zhang, Shuai Hou, Yu Guo, Xiaohui Ma, Hongmei Meng   +7 more
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