Results 61 to 70 of about 1,145,138 (308)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Josiah I. Chung, Nutman, Thomas B, Barnes, MA, Josiah I Chung, Chung, Josiah I, Cooper, Philip J, Meera G. Nair (285902), Josiah I. Chung (682394), Nair, Meera G, Gang Chen (107840), Thomas B. Nutman, Nair, MG, Mali Camberis, Le Gros, G, Graham Le Gros, Mark A. Barnes (682393), Thomas B. Nutman (113195), Le Gros, Graham, Steel, C, Mark A Barnes, Jessica C. Jang (682391), Mitchell A. Lazar, Camberis, M, Thomas B Nutman, Meera G. Nair, Cathy Steel (180788), Jang, JC, Meera G Nair, Graham Le Gros (682396), Cooper, PJ, Jessica C Jang, Spencer H. Wang, Lazar, MA, Mitchell A Lazar, Spencer H. Wang (682392), Lazar, Mitchell A, Mark A. Barnes, Chen, Gang, Camberis, Mali, Mitchell A. Lazar (27888), Wang, SH, Gang Chen, Barnes, Mark A, Chen, G, Spencer H Wang, Philip J. Cooper, Wang, Spencer H, Mali Camberis (682395), Philip J. Cooper (218309), Chung, JI, Nutman, TB, Cathy Steel, Jang, Jessica C, Philip J Cooper, Steel, Cathy, Jessica C. Jang   +55 more
core   +1 more source

Gut microbiota influence acute pancreatitis through inflammatory proteins: a Mendelian randomization analysis

Frontiers in Cellular and Infection Microbiology
Background/AimWe employed Mendelian randomization (MR) analysis to investigate the causal relationship between the gut microbiota, acute pancreatitis, and potential inflammatory proteins.MethodsThe data for gut microbiota, acute pancreatitis, and ...
Peiyao Huang, Qiang Liu, Qiang Liu, Qiang Liu, Tianlong Zhang, Jianfeng Yang, Jianfeng Yang, Jianfeng Yang   +7 more
doaj   +1 more source

Association of Glycated Proteins with Inflammatory Proteins and Periodontal Disease Parameters

Journal of Diabetes Research, 2020
Periodontitis is a chronic inflammatory condition that may contribute to diabetogenesis. The aim was to investigate the levels of glycated proteins and their correlation with periodontal and systemic inflammation.
Jeneen Panezai, Mohammad Altamash, Per-Erik Engstrӧm, Anders Larsson   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anti‑inflammatory and anticoagulant properties of the protein C system in inflammatory bowel disease [PDF]

Polish Archives of Internal Medicine, 2012
In patients with inflammatory bowel disease (IBD), disbalance between procoagulant, anticoagulant, and fibrinolytic factors has been shown. The hemostatic system is an indispensable component of the inflammatory process. Deficiencies in the protein C (PC) pathway components not only promote thrombosis, but also exacerbate inflammation.The aim of the ...
Owczarek, Danuta, Cibor, Dorota, Sałapa, Kinga, Cieśla, Andrzej, Głowacki, Mikołaj, Pocztar, Halina, Mach, Tomasz   +6 more
openaire   +3 more sources

Effect of therapeutic hypothermia on surfactant proteins, anti-inflammatory and pro-fibrotic mediators [PDF]

Objectives To study the effect of hypothermia on surfactant proteins, anti-inflammatory and pro-fibrotic mediators Design Prospective, pragmatic study enrolling asphyxiated neonates without lung injury.
Alonso Eugenio, Alejandro, Touqui, Lhousseine, De Luca, Daniele, Arroyo, Raquel, Autilio, Chiara, Kingma, Paul S., Pérez Gil, Jesús, Foligno, Silvia   +7 more
core   +1 more source

CEACAM6 gene variants in inflammatory bowel disease. [PDF]

, 2011
The carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) acts as a receptor for adherent-invasive E. coli (AIEC) and its ileal expression is increased in patients with Crohn's disease (CD). Given its contribution to the pathogenesis of CD,
Seiderer, J., Darina Czamara, Seiderer Julia, Ochsenkühn, Thomas, Ulrich Lass, Fries, C., Beigel, F., Glas, J., Müller-Myhsok, B., Czamara, D., Bertram Müller-Myhsok, Diegelmann Julia, Fries Christoph, Tillack, Cornelia, Lass, U., Pfennig Simone, Brand, Stephan, Göke, B., Brand Stephan, Thomas Ochsenkühn, Weidinger Maria, Olszak Torsten, Beigel, Florian, Weidinger, Maria, Ochsenkühn, T., Christiane Wolf, Wolf, Christiane, Cornelia Tillack, Julia Diegelmann, Beigel Florian, Müller-Myhsok Bertram, Göke, Burkhard, Lass Ulrich, Fries, Christoph, Pfennig, S., Pfennig, Simone, Peter Lohse, Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Lohse, P., Christoph Fries, Ochsenkühn Thomas, Müller-Myhsok, Bertram, Weidinger, M., Burkhard Göke, Göke Burkhard, Stephan Brand, Wolf, C., Maria Weidinger, Brand, S., Czamara, Darina, Jürgen Glas, Tillack Cornelia, Wolf Christiane, Lass, Ulrich, Czamara Darina, Lohse, Peter, Diegelmann, Julia, Simone Pfennig, Glas Jürgen, Torsten Olszak, Olszak, T., Florian Beigel, Lohse Peter, Julia Seiderer, Olszak, Torsten, Tillack, C.   +67 more
core   +1 more source

Causal relationship between inflammatory proteins and glioblastoma: a two-sample bi‑directional mendelian randomization study

Frontiers in Genetics
Background: Observational studies have indicated a potential correlation between glioblastoma and circulating inflammatory proteins. Further investigation is required to establish a causal relationship between these two factors.Methods: We performed a ...
Xiang Lin, Xiang Lin, Xiang Lin, Wei Gao, Wei Gao, Chen Huang, Minghua Wu, Minghua Wu, Xiaoling She   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source