Results 31 to 40 of about 9,717 (178)

Comparison of H7N9 and H9N2 influenza infections in mouse model unravels the importance of early innate immune response in host protection

Frontiers in Cellular and Infection Microbiology, 2022
The outcome of infection with influenza A virus is determined by a complex virus-host interaction. A new H7N9 virus of avian origin crossed the species barrier to infect humans, causing high mortality and emerged as a potential pandemic threat.
Cuisong Zhu, Cuisong Zhu, Miaomiao Zhang, Weihui Fu, Yongquan He, Yu Yang, Linxia Zhang, Songhua Yuan, Lang Jiang, Jianqing Xu, Jianqing Xu, Xiaoyan Zhang, Xiaoyan Zhang   +12 more
doaj   +1 more source

Influenza A(H7N9) Virus Transmission between Finches and Poultry [PDF]

Emerging Infectious Diseases, 2015
Low pathogenicity avian influenza A(H7N9) virus has been detected in poultry since 2013, and the virus has caused >450 infections in humans. The mode of subtype H7N9 virus transmission between avian species remains largely unknown, but various wild birds have been implicated as a source of transmission.
Jeremy C. Jones, Stephanie Sonnberg, Richard Webby, Robert G. Webster   +3 more
openaire   +3 more sources

Novel avian influenza A (H7N9) virus induces impaired interferon responses in human dendritic cells. [PDF]

PLoS ONE, 2014
In March 2013 a new avian influenza A(H7N9) virus emerged in China and infected humans with a case fatality rate of over 30%. Like the highly pathogenic H5N1 virus, H7N9 virus is causing severe respiratory distress syndrome in most patients.
Veera Arilahti, Sanna M Mäkelä, Janne Tynell, Ilkka Julkunen, Pamela Österlund   +4 more
doaj   +1 more source

Potential Pandemic of H7N9 Avian Influenza A Virus in Human [PDF]

Frontiers in Cellular and Infection Microbiology, 2018
Since 2013, the H7N9 avian influenza A virus (AIV) has caused human infections and to the extent of now surpassing H5N1. This raises an alarm about the potential of H7N9 to become a pandemic problem. Our compilation of the amino acid changes required for AIVs to cross the species-barrier discovers 58 that have very high proportions in both the human ...
Zhiqing Pu, Dan Xiang, Xiaobing Li, Tingting Luo, Xuejuan Shen, Robert W. Murphy, Ming Liao, Ming Liao, Yongyi Shen, Yongyi Shen   +9 more
openaire   +3 more sources

A System Based-Approach to Examine Host Response during Infection with Influenza A Virus Subtype H7N9 in Human and Avian Cells

Cells, 2020
Although the influenza A virus H7N9 subtype circulates within several avian species, it can also infect humans with a severe disease outcome. To better understand the biology of the H7N9 virus we examined the host response to infection in avian and human
Biruhalem Taye, Hui Chen, Dawn Su-Yin Yeo, Shirley Gek-Kheng Seah, Michelle Su-Yen Wong, Richard J Sugrue, Boon-Huan Tan   +6 more
doaj   +1 more source

A Replication-Defective Influenza Virus Vaccine Confers Complete Protection against H7N9 Viral Infection in Mice

Vaccines, 2020
Avian influenza H7N9 viruses continue to pose a great threat to public health, which is evident by their high case-fatality rates. Although H7N9 was first isolated in humans in China in 2013, to date, there is no commercial vaccine available against this
Shelby Landreth, Yao Lu, Kannupriya Pandey, Yan Zhou   +3 more
doaj   +1 more source

Avian influenza A(H7N9) virus screening in patients with fever and flu-like symptoms in a tertiary hospital in an area with confirmed cases. [PDF]

PLoS ONE, 2013
Novel avian influenza A(H7N9) virus was isolated in fatal patients in Yangtze River Delta of China in March 2013. We aimed to screen the virus in febrile patients in a tertiary hospital in an area with confirmed cases.
Chao Wu, Rui Huang, Jianjun Chen, Qin Gu, Bin Zhu, Jun Wang, Kui Zhang, Quanjiao Chen, Chaochao Xiong, Yong Liu, Jiequan Li, Yi-Hua Zhou, Yitao Ding   +12 more
doaj   +1 more source

A highly immunogenic vaccine against A/H7N9 influenza virus [PDF]

Vaccine, 2016
Since the first case of human infection in March 2013, continued reports of H7N9 cases highlight a potential pandemic threat. Highly immunogenic vaccines to this virus are urgently needed to protect vulnerable populations who lack protective immunity.
Weiping, Cao, Justine S, Liepkalns, Ahmed O, Hassan, Ram P, Kamal, Amelia R, Hofstetter, Samuel, Amoah, Jin Hyang, Kim, Adrian J, Reber, James, Stevens, Jacqueline M, Katz, Shivaprakash, Gangappa, Ian A, York, Suresh K, Mittal, Suryaprakash, Sambhara   +13 more
openaire   +2 more sources

H7N9 influenza virus surveillance in Gansu, China in 2017

Virus Research, 2021
Avian H7N9 influenza virus, which emerged in 2013 China, had caused the fifth wave of peaks in 2016-2017. Gansu Province locate in western China far away from the epicenter of the virus, also detected cases in this wave. During the monitoring, five human cases with H7N9 virus infection, three cases in Jiuquan and two cases in Zhangye, were reported and
Baodi, Li, Guofeng, Xiang, Jun, He, Hongyu, Li, Congshan, Xu, Aihong, Yu, Zhe, Zhao, Xueying, Wang, Lihua, Zhang, Hui, Zhang, Huimin, Zhang, Mingjun, Xie, Peng, Wang, Deshan, Yu   +13 more
openaire   +2 more sources

Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin [PDF]

Cell, 2013
The advent of H7N9 in early 2013 is of concern for a number of reasons, including its capability to infect humans, the lack of clarity in the etiology of infection, and because the human population does not have pre-existing immunity to the H7 subtype. Earlier sequence analyses of H7N9 hemagglutinin (HA) point to amino acid changes that predicted human
Tharakaraman, Kannan, Jayaraman, Akila, Raman, Rahul, Viswanathan, Karthik, Stebbins, Nathan W., Johnson, David Alan, Shriver, Zachary H., Sasisekharan, Ram, Stebbins, Nathan W., Sasisekharan, Viswanathan   +9 more
openaire   +4 more sources