Results 11 to 20 of about 9,717 (178)

Avian Influenza H7N9 Virus Adaptation to Human Hosts [PDF]

Viruses, 2021
Avian influenza virus A (H7N9), after circulating in avian hosts for decades, was identified as a human pathogen in 2013. Herein, amino acid substitutions possibly essential for human adaptation were identified by comparing the 4706 aligned overlapping nonamer position sequences (1–9, 2–10, etc.) of the reported 2014 and 2017 avian and human H7N9 ...
Swan Tan, Muhammad Farhan Sjaugi, Siew Chinn Fong, Li Chuin Chong, Hadia Syahirah Abd Raman, Nik Elena Nik Mohamed, Joseph Thomas August, Asif M. Khan   +7 more
openaire   +5 more sources

Supplementation of H7N9 Virus-Like Particle Vaccine With Recombinant Epitope Antigen Confers Full Protection Against Antigenically Divergent H7N9 Virus in Chickens

Frontiers in Immunology, 2022
The continuous evolution of the H7N9 avian influenza virus suggests a potential outbreak of an H7N9 pandemic. Therefore, to prevent a potential epidemic of the H7N9 influenza virus, it is necessary to develop an effective crossprotective influenza ...
Dexin Kong, Dexin Kong, Dexin Kong, Dexin Kong, Taoran Chen, Taoran Chen, Taoran Chen, Taoran Chen, Xiaolong Hu, Xiaolong Hu, Xiaolong Hu, Xiaolong Hu, Shaorong Lin, Shaorong Lin, Shaorong Lin, Shaorong Lin, Yinze Gao, Yinze Gao, Yinze Gao, Yinze Gao, Chunmei Ju, Ming Liao, Ming Liao, Ming Liao, Ming Liao, Huiying Fan, Huiying Fan, Huiying Fan, Huiying Fan   +28 more
doaj   +1 more source

Transcriptome Differences in Normal Human Bronchial Epithelial Cells in Response to Influenza A pdmH1N1 or H7N9 Virus Infection

Cells, 2022
Avian influenza A (H7N9) virus infections frequently lead to acute respiratory distress syndrome and death in humans. The emergence of H7N9 virus infections is a serious public health threat.
Tzu-Hsuan Hsieh, Ya-Jhu Lin, Mei-Jen Hsioa, Hsin-Ju Wang, Lu-Ting Chen, Shu-Li Yang, Chung-Guei Huang   +6 more
doaj   +1 more source

Response of mice and ferrets to a monovalent influenza A (H7N9) split vaccine. [PDF]

PLoS ONE, 2014
In early spring 2013, the emergence of the influenza A (H7N9) virus in humans in Eastern China raised concerns of a new influenza pandemic. Development of a safe and effective H7N9 influenza vaccine is urgently needed.
Yueqiang Duan, Hongjing Gu, Rui Chen, Zhongpeng Zhao, Liangyan Zhang, Li Xing, Chengcai Lai, Peirui Zhang, Zhiwei Li, Keming Zhang, Zhouhai Wang, Shaogeng Zhang, Xiliang Wang, Penghui Yang   +13 more
doaj   +1 more source

Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity. [PDF]

PLoS ONE, 2015
Influenza virus is a source of significant health and economic burden from yearly epidemics and sporadic pandemics. Given the potential for the emerging H7N9 influenza virus to cause severe respiratory infections and the lack of exposure to H7 and N9 ...
Sean R McMaster, Jon D Gabbard, Dimitris G Koutsonanos, Richard W Compans, Ralph A Tripp, S Mark Tompkins, Jacob E Kohlmeier   +6 more
doaj   +1 more source

Poultry to Human Passport: Cross-species Transmission of Zoonotic H7N9 Avian Influenza Virus to Humans

Zoonoses, 2022
Human infections with H7N9 avian influenza virus were first reported in the early spring of 2013, in the Yangtze-delta region of China. This virus subsequently caused five successive epidemic waves from 2013 to 2018 with highest reported cases in the ...
Yongkun Chen, Tian Bai, Yuelong Shu
doaj   +1 more source

Evaluation of Commercial Diagnostic Assays for the Specific Detection of Avian Influenza A (H7N9) Virus RNA Using a Quality-Control Panel and Clinical Specimens in China. [PDF]

PLoS ONE, 2015
A novel avian influenza A H7N9-subtype virus emerged in China in 2013 and threatened global public health. Commercial kits that specifically detect avian influenza A (H7N9) virus RNA are urgently required to prepare for the emergence and potential ...
Dawei Shi, Shu Shen, Xingliang Fan, Suhong Chen, Dayan Wang, Changgui Li, Xing Wu, Lili Li, Dongting Bai, Chuntao Zhang, Junzhi Wang   +10 more
doaj   +1 more source

Antigenic Characterization of Neuraminidase of Influenza A/H7N9 Viruses Isolated in Different Years

Pharmaceuticals, 2022
Influenza outbreaks caused by A/H7N9 viruses have occurred since 2013. After 2016, A/H7N9 influenza viruses underwent evolutionary changes. In this study, we examined the antigenic properties of influenza neuraminidase (NA) of A/H7N9 viruses as part of a
Yulia Desheva, Igor Losev, Nadezhda Petkova, Polina Kudar, Svetlana Donina, Andrey Mamontov, Chih-Hsuan Tsai, Yu-Chan Chao   +7 more
doaj   +1 more source

Surveillance of Influenza A Virus and Its Subtypes in Migratory Wild Birds of Nepal. [PDF]

PLoS ONE, 2015
Nepal boarders India and China and all three countries lie within the Central Asian Flyway for migratory birds. Novel influenza A H7N9 caused human fatalities in China in 2013.
Dibesh Karmacharya, Sulochana Manandhar, Ajay Sharma, Tarka Bhatta, Pratikshya Adhikari, Adarsh Man Sherchan, Bishwo Shrestha, Manisha Bista, Rajesh Rajbhandari, Mohinder Oberoi, Khadak Bisht, Jean-Marc Hero, Ravi Dissanayake, Maheshwar Dhakal, Jane Hughes, Nitish Debnath   +15 more
doaj   +1 more source

The pandemic potential of avian influenza A(H7N9) virus: a review [PDF]

Epidemiology and Infection, 2015
SummaryIn March 2013 the first cases of human avian influenza A(H7N9) were reported to the World Health Organization. Since that time, over 650 cases have been reported. Infections are associated with considerable morbidity and mortality, particularly within certain demographic groups.
W. D. TANNER, D. J. A. TOTH, A. V. GUNDLAPALLI   +2 more
openaire   +2 more sources