Results 21 to 30 of about 31,937 (255)

Determinants of Antiviral Effectiveness in Influenza Virus A Subtype H5N1 [PDF]

Journal of Infectious Diseases, 2012
Oseltamivir is widely used as treatment for influenza virus A subtype H5N1 (hereafter, "H5N1") infection but, like any intervention, is not always effective.We used Avian Influenza Registry data from 10 countries to examine the risk of death in 215 patients with confirmed H5N1 infection who were treated with oseltamivir, according to viral clade, age ...
Dreyer, Nancy A., Zaman, Mukhtiar, Hanshaoworakul, Wanna, Chan, Paul K. S., Gasimov, Viktor, Toovey, Stephen, Lee, Nelson, Oner, Ahmet Faik, Tsang, Owen, Phommasack, Bounlay, Coker, Richard, Adisasmito, Wiku, Touch, Sok, Bamgboye, Ebun, Swenson, Anna, DOĞAN, Nazim   +15 more
openaire   +4 more sources

Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1 [PDF]

Journal of Virological Methods, 2011
The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast Asia, but also in several European countries. Effective diagnosis and control measures are essential for the management of HPAIV infections. To develop a
Linke, Sonja, Neubauer, Katrin, Dorner, Martin, Dorner, Brigitte, Pauli, Georg, Schweiger, Brunhilde   +5 more
openaire   +3 more sources

Avian influenza overview September-November 2025. [PDF]

EFSA J
Abstract Between 6 September and 28 November 2025, 2896 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in domestic (442) and wild (2454) birds in 29 countries in Europe. The magnitude and geographical extent of these detections were unprecedented for this time of the year, particularly in wild birds.
European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Buczkowski H, Ducatez M, Fusaro A, Gonzales JL, Kuiken T, Mirinavičiūtė G, Ståhl K, Staubach C, Svartström O, Terregino C, Willgert K, Alarcón E, Kohnle L.   +15 more
europepmc   +2 more sources

Highly Pathogenic Avian Influenza Virus (H5N1) Clade 2.3.4.4b Introduced by Wild Birds, China, 2021

Emerging Infectious Diseases, 2023
Highly pathogenic avian influenza (HPAI) subtype H5N1 clade 2.3.4.4b virus has spread globally, causing unprecedented large-scale avian influenza outbreaks since 2020. In 2021, we isolated 17 highly pathogenic avian influenza H5N1 viruses from wild birds
Jingman Tian, X. Bai, Minghui Li, Xianying Zeng, Jia Xu, Peng Li, Miao-ruo Wang, Xingdong Song, Zhiguo Zhao, G. Tian, Liling Liu, Y. Guan, Yanbing Li, Hualan Chen   +13 more
semanticscholar   +1 more source

A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. [PDF]

PLoS ONE, 2011
Development of effective vaccines to prevent influenza, particularly highly pathogenic avian influenza (HPAI) caused by influenza A virus (IAV) subtype H5N1, is a challenging goal.
Lanying Du, Virtual Ho-Chuen Leung, Xiujuan Zhang, Jie Zhou, Min Chen, Wu He, Hai-Ying Zhang, Chris C S Chan, Vincent Kwok-Man Poon, Guangyu Zhao, Shihui Sun, Lifeng Cai, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang   +14 more
doaj   +1 more source

In silico QSAR and molecular docking simulation of some novel aryl sulfonamide derivatives as inhibitors of H5N1 influenza A virus subtype

Beni-Suef University Journal of Basic and Applied Sciences, 2020
This research provides a comprehensive analysis of QSAR modeling performed on 25 aryl sulfonamide derivatives to predict their effective concentration (EC50) against H5N1 influenza A virus by using some numerical information derived from structural and ...
Mustapha Abdullahi, Gideon Adamu Shallangwa, A. Uzairu   +2 more
semanticscholar   +1 more source

H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry

Microbiology Spectrum, 2021
Highly pathogenic avian influenza (HPAI) H5 viruses have posed a substantial pandemic threat through repeated human infection since their emergence in China in 1996. Nationwide control measures, including vaccination of poultry, were implemented in 2005,
Yao-Tsun Li, Yvonne C. F. Su, Gavin J. D. Smith   +2 more
doaj   +1 more source

Whole-genome sequence and genesis of an avian influenza virus H5N1 isolated from a healthy chicken in a live bird market in Indonesia: accumulation of mammalian adaptation markers in avian hosts [PDF]

PeerJ, 2023
Background Influenza A viruses are a major pathogen that causes significant clinical and economic harm to many animals. In Indonesia, the highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in poultry since 2003 and has caused sporadic ...
Saifur Rehman, Rima Ratnanggana Prasetya, Krisnoadi Rahardjo, Mustofa Helmi Effendi, Fedik Abdul Rantam, Jola Rahmahani, Adiana Mutamsari Witaningrum, Aldise Mareta Nastri, Jezzy Renova Dewantari, Yasuko Mori, Kazufumi Shimizu   +10 more
doaj   +2 more sources

Deteksi, Isolasi, dan Identifikasi Avian influenza Subtipe H5N1 pada Unggas di Pulau Jawa, Indonesia Tahun 2016 (DETECTION, ISOLATION AND IDENTIFICATION OF H5N1 SUBTYPE AVIAN INFLUENZA IN POULTRY IN JAVA ISLAND, INDONESIA, 2016)

Jurnal Veteriner, 2018
H5N1 subtype Avian influenza has harmed for poultry in Indonesia currently. Since clade 2.3.2 Avian influenza has been found in waterfowl from 2012, mortality of waterfowl has been occured until now. Change of extreme weather condition with high rainfall
Dyah Ayu Hewajuli, Ni Luh Putu Indi Dharmayanti, I Wayan Teguh Wibawan   +2 more
doaj   +1 more source

Cross-subtype Immunity against Avian Influenza in Persons Recently Vaccinated for Influenza

Emerging Infectious Diseases, 2008
Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune cross-reactivity between human and avian influenza (H5N1) strains in healthy donors vaccinated for ...
Cristiana Gioia, Concetta Castilletti, Massimo Tempestilli, Paola Piacentini, Licia Bordi, Roberta Chiappini, Chiara Agrati, Salvatore Squarcione, Giuseppe Ippolito, Vincenzo Puro, Maria Rosaria Capobianchi, Fabrizio Poccia   +11 more
doaj   +1 more source