Results 181 to 190 of about 11,867,541 (291)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

A pesquisa discente nos cursos de graduação em biblioteconomia e ciência da informação

Transinformação
Discute-se a importância da pesquisa discente nos cursos de graduação em Biblioteconomia e Ciência da Informação. Enfocam-se os diferentes tipos e os níveis de participação dos alunos em projetos de pesquisa.
César Augusto Castro
doaj  

Assessment of the use of Open Educational Resources at five European Library and Information Science higher education institutions during and post-COVID-19 pandemic. [PDF]

Open Res Eur
Santos-Hermosa G, Urbano C, Argudo S, Boté-Vericad JJ, Đurđevic A, Micunovic M, Wöbbekind L, Todorova T.   +7 more
europepmc   +1 more source

Computer Science vs Information Technology [PDF]

, 2014
Khar, A.T., Shulgin, Nikita, Zuyenok, I.I.   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Newsletter [PDF]

, 1991
International Association of Aquatic and Marine Science Libraries and Information Centers
core   +3 more sources

Educational strategies related to information science and technology for medical students: General medicine physicians' perspective. [PDF]

J Gen Fam Med
Shikino K, Tago M, Watari T, Sasaki Y, Takahashi H, Shimizu T.   +5 more
europepmc   +1 more source

Information Science [PDF]

, 2019
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Repositioning the Chemical Information Science Gateway. [PDF]

F1000Res, 2019
Bajorath J.
europepmc   +1 more source