Results 71 to 80 of about 94,856 (286)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Detection of humidity ingress using online common-mode insulation impedance-monitoring system
The Journal of Engineering, 2019 Enhanced machine reliability through monitoring of its state of health is an emerging field of research. Ingress of contaminants such as moisture can effect electrical machine state of health and contribute to failure in winding insulation.
Igor Tsyokhla +3 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Asymmetry in zeta Auriage chromospheres [PDF]
Asymmetry in the ultraviolet spectra of zeta-Aur, similar to that reported in optical observations, was studied using IUE data. A plot of the integrated flux of zeta Aurigae from 1625 to 1675 A as a function of absolute phase shows no significant ...
Ahmad, I. A.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Modelling of chloride ingress in concrete based on benchmarking field results
MATEC Web of Conferences, 2018 Modelling the ingress of chloride ions into the cover of a concrete structure is a phenomenon that is gaining an increasing attention of the research community, but even more, from the engineering practice.
Koenders E.A.B.
doaj +1 more source
, 2004 A transiting extrasolar planet sequentially blocks off the light coming from the different parts of the disk of the host star in a time dependent manner.
Atsushi Taruya +13 more
core +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Theoretical modelling of hot gas ingestion through turbine rim seals
Propulsion and Power Research, 2012 The rim seals of gas turbines are used to prevent or reduce the ingestion of hot mainstream gas into the wheel-space between the turbine rotor and its adjacent stationary casing.
J. Michael Owen
doaj +1 more source