Results 21 to 30 of about 64,020 (238)
Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages. [PDF]
PLoS ONE, 2011 Hemorrhagic meningitis is a fatal complication of anthrax, but its pathogenesis remains poorly understood. The present study examined the role of B.
Dhritiman V Mukherjee +7 more
doaj +1 more source
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain [PDF]
, 2015 The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB) pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy and when transmission of resistant strains on a larger scale became a
Balloux, Francois +6 more
core +4 more sources
Advances and Applications in Bioinformatics and Chemistry, 2023 Purpose The enoyl-acyl carrier protein reductase (InhA) is one of the important key enzymes employed in mycolic acids biosynthesis pathway and an important component of mycobacterial cell walls.
Ghyzlane El Haddoumi +6 more
semanticscholar +1 more source
Biochemistry, 2023 InhA, the Mycobacterium tuberculosis enoyl-ACP reductase, is a target for the tuberculosis (TB) drug isoniazid (INH). InhA inhibitors that do not require KatG activation avoid the most common mechanism of INH resistance, and there are continuing efforts ...
S. Davoodi +8 more
semanticscholar +1 more source
Pion properties at finite density [PDF]
, 2008 In this talk, we report our recent work on the pion weak decay constant (F_pi) and pion mass (m_pi) using the nonlocal chiral quark model with the finite quark-number chemical potential (mu) taken into account.
HYUN-CHUL KIM, Kim H. C., SEUNG-IL NAM
core +1 more source
Absence of inhibin alpha and retinoblastoma protein leads to early sertoli cell dysfunction. [PDF]
PLoS ONE, 2010 Sertoli cells, the support cells of mammalian spermatogenesis, are regulated by a number of nuclear factors and express retinoblastoma (RB) tumor suppressor protein.
Roopa L Nalam +2 more
doaj +1 more source
Microbiology Spectrum, 2022 The emergence of antimicrobial resistance warrants for the development of improved treatment approaches. In this regard, peptide nucleic acids (PNAs) have shown great promise, exhibiting antibiotic properties through the targeting of cellular nucleic ...
Karishma Berta Cotta +2 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2019 Anti-tubercular therapy is one of the effective strategies used to control tuberculosis, so, a planned and accurate treatment regimen is of utmost importance, but number of cases are being treated as MDR on the basis of rifampicin mono resistance.
Sana Nudrat, Umar Farooq, Mazhar Maqsood
doaj +1 more source
Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice. [PDF]
PLoS ONE, 2011 Inhibin is an important marker of Sertoli cell (SC) activity in animals with impaired spermatogenesis. However, the precise relationship between inhibin and SC activity is unknown.
Kailai Cai +7 more
doaj +1 more source
Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636 [PDF]
, 2008 The identification of potential new anti-tubercular cemotherapeutics is paramount due to the recent emergence of extensively drug-resistant strains of Mycobacterium tuberculosis (XDR-TB).Libraries of NAS-21 and NAS-91 analogues were synthesized and ...
Besra, Gurdyal S +2 more
core +2 more sources