Results 141 to 150 of about 11,084 (293)

Anesthesia and sustainability: inhalation anesthetics.

open access: yes
Justification of the Work Inhalational anesthetics remain important pharmacologic agents used by anesthesiologists to induce general anesthesia.
Činčikas, Mindaugas Titas,
core  

Expert Perspectives: Defining and managing progressive pulmonary fibrosis in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
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Devis Benfaremo   +7 more
wiley   +1 more source

How do General Anesthetics Work?

open access: yes, 2019
General anesthesia is one of the most important advances in medical history allowing the execution of medical procedures that would be too painful to tolerate for conscious patients. Despite over 170 years of general clinical practice in Western medicine,
Türkyılmaz, Serhan
core   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop   +3 more
wiley   +1 more source

Effects of anesthesia on conventional and speckle tracking echocardiographic parameters in a mouse model of pressure overload

open access: yes, 2015
Genetically‑modified mice are widely applied in cardiovascular studies as model organisms. Echocardiography is a key tool for evaluating cardiac and hemodynamic functions in mice.
Wu, Xiaofen   +7 more
core   +1 more source

Goal Displacement and Goal Conflicts in Circular Innovation Initiatives: Types and Mitigation Practices

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim   +2 more
wiley   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

Influence of inhalation anesthetics on a model biological membrane

open access: yes, 2019
General anesthesia is defined as impairment of the central nervous system (UON) caused by intravenous or volatile anesthetics. The state of loss of consciousness or even amnesia and the disappearance of perception into external stimuli is achieved by the
Rospenk, Maria   +2 more
core  

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