Results 31 to 40 of about 742,740 (307)
Digital Chinese Medicine, 2019 Objective: To identify the compounds with α-glucosidase inhibitory activity from Clerodendrum bungei Steud (Chou Mu Dan, 臭牡丹) using HPLC-ESI-QTOF-MS/MS.
Huang Xiao-Long +5 more
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Application of QSAR models in analysis of antibacterial activity of some benzimidazole derivatives against Sarcina lutea [PDF]
Hemijska Industrija, 2013 In the present paper, a quantitative structure activity relationship (QSAR) has been carried out on a series of 2-methyl and 2-aminobenzimidazole derivatives to identify the lipophilicity requirements for their inhibitory activity against bacteria ...
Podunavac-Kuzmanović Sanja O. +3 more
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Research in Pharmaceutical Sciences, 2021 Background and purpose: Alzheimer’s disease is considered one of the lead causes of elderly death around the world. A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer’s disease, therefore ...
Motahareh Hassanzadeh +6 more
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Natural Compounds with Aromatase Inhibitory Activity: An Update [PDF]
Planta Medica, 2010 Several synthetic aromatase inhibitors are currently in clinical use for the treatment of postmenopausal women with hormone-receptor positive breast cancer. However, these treatments may lead to untoward side effects and so the search for new aromatase inhibitors continues, especially those for which the activity is promoter-specific, targeting the ...
Marcy J, Balunas, A Douglas, Kinghorn
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Acta Universitatis Cibiniensis. Series E: Food Technology, 2020 The bioaccessible angiotensin converting enzyme (ACE) inhibitory activity of biscuits formulated from roasted common buckwheat flour after fermentation by select bacteria was studied.
Wronkowska Małgorzata +3 more
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BMC Chemistry, 2020 In this study, 5-amino-nicotinic acid derivatives (1–13) have been designed and synthesized to evaluate their inhibitory potential against α-amylase and α-glucosidase enzymes.
Muhammad Nawaz +8 more
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Synthesis and Activity Evaluation of Vinpocetine-Derived Indole Alkaloids
Molecules, 2023 This study focuses on the synthesis of novel vinpocetine derivatives (2–25) and their biological evaluation. The chemical structures of the synthesized compounds were fully characterized using techniques such as 1H NMR, 13C NMR, and HRMS.
Zhang-Chao Dong +7 more
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Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]
, 2019 New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone +8 more
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Aldose Reductase Inhibitory Compounds from Glycyrrhiza uralensis
Biological and Pharmaceutical Bulletin, 2010 We evaluated the inhibitory effects of components from the root of Glycyrrhiza uralensis (G. uralensis) on aldose reductase (AR) and sorbitol formation in rat lenses with high levels of glucose as part of our ongoing search of natural sources for therapeutic and preventive agents for diabetic complications. In order to identify the bioactive components
Yeon Sil, Lee +5 more
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Molecules, 2020 Previous studies have reported that Hedyotis diffusa Willdenow extract shows various biological activities on cerebropathia, such as neuroprotection and short-term memory enhancement.
Jun Hee Park, Wan Kyunn Whang
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