Results 11 to 20 of about 749,302 (307)
Thrombin inhibitory activity of some polyphenolic compounds [PDF]
Medicinal Chemistry Research, 2013 Thrombin, also known as an active plasma coagulation factor II, belongs to the family of serine proteases and plays a crucial role in blood coagulation process. The process of thrombin generation is the central event of the hemostatic process and regulates blood coagulant activity.
Bijak, M. +7 more
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Inhibition of SARS-CoV 3CL protease by flavonoids
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required.
Seri Jo +3 more
doaj +1 more source
Compounds from Gum Ammoniacum with Acetylcholinesterase Inhibitory Activity [PDF]
Scientia Pharmaceutica, 2013 The use of herbal medicinal preparations in dementia therapy has been studied based on experience from traditional medicine. A dichloromethane extract of gum ammoniacum, the gum-resin from Dorema ammoniacum D. Don had shown acetylcholinesterase (AChE) inhibitory activity in a previous study.
Adhami, Hamid-Reza +4 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 In this paper, bis (indol-3-yl) methanes (BIMs) were synthesised and evaluated for their inhibitory activity against α-glucosidase and α-amylase. All synthesised compounds showed potential α-glucosidase and α-amylase inhibitory activities. Compounds 5 g (
Peng-Fei Zheng +10 more
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NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy
Plants, 2022 Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng +5 more
doaj +1 more source
Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Coronavirus disease 2019 (COVID-19) has been a pandemic disease of which the termination is not yet predictable. Currently, researches to develop vaccines and treatments is going on globally to cope with this disastrous disease.
Seri Jo +4 more
doaj +1 more source
Assessment of landfill leachate biodegradability and treatability by means of allochthonous and autochthonous biomasses [PDF]
, 2020 The biodegradability and treatability of a young (3 years old) municipal landfill leachate was evaluated by means of chemical oxygen demand (COD) fractionation tests, based on respirometric techniques.
Corsino, S.F., Capodici, M., Di Trapani, D., Torregrossa Michele, Viviani Gaspare
core +1 more source
Inhibition of African swine fever virus protease by myricetin and myricitrin
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 African swine fever (ASF) caused by the ASF virus (ASFV) is the most hazardous swine disease. Since a huge number of pigs have been slaughtered to avoid a pandemic spread, intense studies on the disease should be followed quickly. Recent studies reported
Seri Jo +3 more
doaj +1 more source
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
, 2016 Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
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Laccases as a Potential Tool for the Efficient Conversion of Lignocellulosic Biomass: A Review
Fermentation, 2017 The continuous increase in the world energy and chemicals demand requires the development of sustainable alternatives to non-renewable sources of energy.
Úrsula Fillat +5 more
doaj +1 more source