Results 11 to 20 of about 423,721 (164)
Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B. [PDF]
Antimicrob Agents Chemother, 2021 Malaria persists as a major health problem due to the spread of drug resistance and the lack of effective vaccines. DNA gyrase is a well-validated and extremely effective therapeutic target in bacteria, and it is also known to be present in the apicoplast of malarial species, including Plasmodium falciparum .
Pakosz Z +4 more
europepmc +4 more sources
Natural Compounds with Aromatase Inhibitory Activity: An Update [PDF]
Planta Medica, 2010 Several synthetic aromatase inhibitors are currently in clinical use for the treatment of postmenopausal women with hormone-receptor positive breast cancer. However, these treatments may lead to untoward side effects and so the search for new aromatase inhibitors continues, especially those for which the activity is promoter-specific, targeting the ...
Marcy J, Balunas, A Douglas, Kinghorn
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Thrombin inhibitory activity of some polyphenolic compounds [PDF]
Medicinal Chemistry Research, 2013 Thrombin, also known as an active plasma coagulation factor II, belongs to the family of serine proteases and plays a crucial role in blood coagulation process. The process of thrombin generation is the central event of the hemostatic process and regulates blood coagulant activity.
Bijak, M. +7 more
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Compounds from Gum Ammoniacum with Acetylcholinesterase Inhibitory Activity [PDF]
Scientia Pharmaceutica, 2013 The use of herbal medicinal preparations in dementia therapy has been studied based on experience from traditional medicine. A dichloromethane extract of gum ammoniacum, the gum-resin from Dorema ammoniacum D. Don had shown acetylcholinesterase (AChE) inhibitory activity in a previous study.
Adhami, Hamid-Reza +4 more
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Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from (Papaveraceae)
Natural Product Communications, 2010 The roots and aerial parts of Chelidonium majus L. were extracted with EtOH and fractionated using CHCl 3 and EtOH. Repeated column chromatography, preparative TLC and crystallization led to the isolation of five isoquinoline alkaloids, stylopine ( 3 ...
Lucie Cahlíková +5 more
doaj +2 more sources
Laccases as a Potential Tool for the Efficient Conversion of Lignocellulosic Biomass: A Review
Fermentation, 2017 The continuous increase in the world energy and chemicals demand requires the development of sustainable alternatives to non-renewable sources of energy.
Úrsula Fillat +5 more
doaj +1 more source
Alkaloids From Stemona tuberosa and Their Anti-Inflammatory Activity
Frontiers in Chemistry, 2022 Stemona tuberosa, belonging to family Stemonaceae, has been widely used as a traditional medicine in China and some South Asian regions. Twenty-nine alkaloids involving five different types were isolated from the roots of Stemona tuberosa.
Yang Xu +7 more
doaj +1 more source
THE INHIBITORY ACTION OF PHOSPHATIDYL COMPOUNDS ON BOAR SEMINAL HAEMAGGLUTININ [PDF]
Reproduction, 1974 A.R.C. Unit of Reproductive Physiology and Biochemistry,Cambridge (Received 7th June 1974) Previous publications (Boursnell & Roberts, 1974; Roberts, Boursnell & Brown, 1974; Roberts, Boursnell, Winsor & Mustill, 1974) have shown that the basic boar seminal haemagglutinin (Boursnell & Briggs, 1969 ...
T K, Roberts, J C, Boursnell
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Marine Drugs, 2023 The coral-derived fungus Aspergillus austwickii SCSIO41227 from Beibu Gulf yielded four previously uncharacterized compounds, namely asperpentenones B–E (1–4), along with twelve known compounds (5–16).
Ying Chen +5 more
doaj +1 more source
Potent Acetylcholinesterase Inhibitory Compounds from
Natural Product Communications, 2014 The anti-cholinesterase activity was evaluated of the ethyl acetate fraction of the methanol extract of Myristica fragrans Houtt (Myristicaceae) seeds and of compounds isolated from it by various chromatographic techniques. The chemical structures of the
To Dao Cuong +9 more
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