Results 61 to 70 of about 141,083 (247)

Memory formation in reversal learning of the honeybee

Frontiers in Behavioral Neuroscience, 2010
In reversal learning animals are first trained with a differential learning protocol, where they learn to respond to a reinforced odor (CS+) and not to respond to a nonreinforced odor (CS-).
Ravit Hadar, Randolf Menzel
doaj   +1 more source

Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites

International Journal for Parasitology: Drugs and Drug Resistance, 2023
Malaria, an infectious disease with a tremendous impact on human health is caused by Plasmodium parasites, and transmitted by Anopheles mosquitoes.
Elena Deligianni, Elisabetta Pizzi, Ioanna Kavelaki, Inga Siden-Kiamos, Filippo Umberto Sapienza, Rossella Fioravanti, Stefania Garzoli, Tomasino Pace, Marta Ponzi, Rino Ragno, Chiara Currà   +10 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

When to hold that thought: an experimental study showing reduced inhibition of pre-trained associations in schizophrenia.

PLoS ONE, 2012
Schizophrenia encompasses a wide variety of cognitive dysfunctions, a number of which can be understood as deficits of inhibition. To date, no research has examined 'conditioned inhibition' in schizophrenia--the ability of a stimulus that signals the ...
Zhimin He, Helen J Cassaday, S Bert G Park, Charlotte Bonardi   +3 more
doaj   +1 more source

Time and Inhibitory Learning

, 2011
Associative theories of learning state that an organism acquires new behaviors when associations are formed between a Conditioned Stimulus (CS) and an Unconditioned Stimulus (US). Alternative theories suggest that learning is not reliant on associations between stimuli, but rather on the temporal information conveyed by stimuli. Studies have shown that
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Determintion of the acute and persistant effects of Aluminium on memory and learning Abilities of rat [PDF]

Journal of Kerman University of Medical Sciences, 2001
In regard to the role of Aluminium in the emergence of psychological disorded in patients with chronic kidney diseases,this research project studied the acute,and chronic effects of Alluminium on different stages of memory and learning abilitis,after ...
H. Alaei, A.A Moshtaghi, KH Rezaei
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source