Results 61 to 70 of about 1,294,563 (307)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Cell type specific connections from primary motor to primary somatosensory cortex. [PDF]
, 2013 Anatomical studies have shown that primary somatosensory (S1) and primary motor (M1) cortices are reciprocally connected. The pathway from primary motor cortex (M1) to primary somatosensory cortex (S1) is thought to influence activity in S1 by ...
Kinnischtzke, Amanda K
core
Inhibitory networks of the amygdala for emotional memory
Frontiers in Neural Circuits, 2013 The amygdala is important for emotional memory, including learned fear. A number of studies for amygdala neural circuits that underlie fear conditioning have elucidated specific cellular and molecular mechanisms of emotional memory.
Seungho eLee +4 more
doaj +1 more source
Frontiers in Neural Circuits, 2023 Despite the importance of postsynaptic inhibitory circuitry targeted by mid/long-range projections (e.g., top-down projections) in cognitive functions, its anatomical properties, such as laminar profile and neuron type, are poorly understood owing to the
Yusuke Atsumi +11 more
doaj +1 more source
Patterns of synchronization in 2D networks of inhibitory neurons
Frontiers in Computational Neuroscience, 2022 Neural firing in many inhibitory networks displays synchronous assembly or clustered firing, in which subsets of neurons fire synchronously, and these subsets may vary with different inputs to, or states of, the network. Most prior analytical and computational modeling of such networks has focused on 1D networks or 2D networks with symmetry (often ...
Jennifer Miller +4 more
openaire +4 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
GABAergic inhibition controls neural gain in inferior colliculus neurons sensitive to interaural time differences [PDF]
, 2005 We investigated the role of GABAergic inhibition on the responses of inferior colliculus (IC) neurons sensitive to interaural time differences (ITDs) in anesthetized guinea pigs.
Ingham, NJ, Mcalpine, D
core
Projection neurons in lamina III of the rat spinal cord are selectively innervated by local dynorphin-containing excitatory neurons [PDF]
, 2012 Large projection neurons in lamina III of the rat spinal cord that express the neurokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents. However, we know little about
Todd, A.J. +6 more
core +1 more source
Frontiers in Neural Circuits, 2012 The rat primary somatosensory cortex (S1) is remarkable for its conspicuous vertical compartmentalization in barrels and septal columns, which are additionally stratified in horizontal layers.
Anaelli A Nogueira-Campos +5 more
doaj +1 more source
PAIN Reports, 2021 . Introduction:. Inhibitory neurons in the spinal dorsal horn can be classified based on expression of neurochemical marker genes. However, these marker genes are often expressed throughout the central nervous system, which poses challenges for ...
Elizabeth K. Serafin +3 more
doaj +1 more source