Results 41 to 50 of about 428,396 (292)
Nature Communications, 2021 Here the authors show in a model of ALS that motor neurons receive stronger inhibitory synaptic inputs than slow motor neurons, and disease progression is associated with specific loss of inhibitory synapses onto fast motor neurons.
Ilary Allodi +4 more
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Spatio-Temporal Sequential Memory Model With Mini-Column Neural Network
Frontiers in Neuroscience, 2021 Memory is an intricate process involving various faculties of the brain and is a central component in human cognition. However, the exact mechanism that brings about memory in our brain remains elusive and the performance of the existing memory models is
Yawen Lan +3 more
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Nanodiamonds-induced effects on neuronal firing of mouse hippocampal microcircuits [PDF]
, 2018 Fluorescent nanodiamonds (FND) are carbon-based nanomaterials that can efficiently incorporate optically active photoluminescent centers such as the nitrogen-vacancy complex, thus making them promising candidates as optical biolabels and drug-delivery ...
Battiato, A. +14 more
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Neuronal activity regulates neurotransmitter switching in the adult brain following light-induced stress. [PDF]
, 2018 Neurotransmitter switching in the adult mammalian brain occurs following photoperiod-induced stress, but the mechanism of regulation is unknown. Here, we demonstrate that elevated activity of dopaminergic neurons in the paraventricular nucleus of the ...
Deisseroth, Karl +4 more
core +1 more source
Cannabinoid signaling in inhibitory autaptic hippocampal neurons [PDF]
Neuroscience, 2009 Depolarization-induced suppression of excitation and inhibition (DSE/DSI) appears to be an important form of short-term retrograde neuronal plasticity involving endocannabinoids (eCBs), the activation of presynaptic cannabinoid CB1 receptors, and the suppression of neurotransmitter release.
A, Straiker, K, Mackie
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The Mammalian Interaural Time Difference Detection Circuit Is Differentially Controlled by GABAB Receptors during Development [PDF]
, 2010 Throughout development GABAB receptors (GABABRs) are widely expressed in the mammalian brain. In mature auditory brainstem neurons, GABABRs are involved in the short-term regulation of the strength and dynamics of excitatory and inhibitory inputs, thus ...
Grothe, Benedikt +2 more
core +1 more source
Inhibitory networks of the amygdala for emotional memory
Frontiers in Neural Circuits, 2013 The amygdala is important for emotional memory, including learned fear. A number of studies for amygdala neural circuits that underlie fear conditioning have elucidated specific cellular and molecular mechanisms of emotional memory.
Seungho eLee +4 more
doaj +1 more source
Cell-type-specific responses to associative learning in the primary motor cortex
eLife, 2022 The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements.
Candice Lee +4 more
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Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning. [PDF]
, 2015 Motor skill learning induces long-lasting reorganization of dendritic spines, principal sites of excitatory synapses, in the motor cortex. However, mechanisms that regulate these excitatory synaptic changes remain poorly understood.
Chen, Simon X +3 more
core
Resonant Synchronization in Heterogeneous Networks of Inhibitory Neurons [PDF]
The Journal of Neuroscience, 2003 Brain rhythms arise through the synchronization of neurons and their entrainment in a regular firing pattern. In this process, networks of reciprocally connected inhibitory neurons are often involved, but what mechanism determines the oscillation frequency is not completely understood.
Maex, Reinoud, De Schutter, Erik
openaire +3 more sources