Results 41 to 50 of about 1,294,563 (307)
Frontiers in Molecular Neuroscience, 2022 A large body of studies has investigated bidirectional homeostatic plasticity both in vitro and in vivo using numerous pharmacological manipulations of activity or behavioral paradigms.
Lior Bar +4 more
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The influence of GABAergic signaling on dendritic processing [PDF]
, 2013 GABAergic (?-aminobutyric acid-releasing) signaling plays a crucial role in integration processes of pyramidal neurons. Specific subtypes of GABA releasing interneurons innervate different compartments of pyramidal neurons; thereby modulating the ...
Willadt, Silvia
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Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory
Frontiers in Molecular Neuroscience, 2021 Increasing evidence supports a model whereby memories are encoded by sparse ensembles of neurons called engrams, activated during memory encoding and reactivated upon recall.
Corinna Giorgi +2 more
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Post-Inhibitory Rebound Firing of Dorsal Root Ganglia Neurons
, 2022 Tong Zhu,1,2 Siqi Wei,1 Yuying Wang1,3,4 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Clinical Experimental Center ...
Wei S, Wang Y, Zhu T
core
Cell Reports, 2019 Summary: The canonical cortical microcircuit has principally been defined by interlaminar excitatory connections among the six layers of the neocortex.
Jaclyn Ellen Frandolig +7 more
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CHAOS AND STABILITY IN A MODEL OF INHIBITORY NEURONAL NETWORK [PDF]
International Journal of Bifurcation and Chaos, 2010 We analyze the dynamics of a deterministic model of inhibitory neuronal networks proving that the discontinuities of the Poincaré map produce a never empty chaotic set, while its continuity pieces produce stable orbits. We classify the systems in three types: the almost everywhere (a.e.) chaotic, the a.e. stable, and the combined systems.
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Electrical activity suppresses intrinsic growth competence in adult primary sensory neurons [PDF]
, 2009 The ability of neurons to regenerate in the adult mammalian central nervous system (CNS) is often poor, leading to persistent deficits after injury. Failure of axon regeneration in the CNS has been attributed to the presence of an extrinsic inhibitory ...
Enes, Joana
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eLife, 2016 Dravet Syndrome is an intractable form of childhood epilepsy associated with deleterious mutations in SCN1A, the gene encoding neuronal sodium channel Nav1.1.
Yishan Sun +17 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source