Results 21 to 30 of about 248,879 (259)

Inhibitory Interplay between Orexin Neurons and Eating [PDF]

open access: yesCurrent Biology, 2016
In humans and rodents, loss of brain orexin/hypocretin (OH) neurons causes pathological sleepiness [1-4], whereas OH hyperactivity is associated with stress and anxiety [5-10]. OH cell control is thus of considerable interest. OH cells are activated by fasting [11, 12] and proposed to stimulate eating [13].
González, JA   +5 more
openaire   +3 more sources

Function of Dendritic Spines on Hippocampal Inhibitory Neurons [PDF]

open access: yesCerebral Cortex, 2013
The majority of γ-aminobutyric acid (GABA)ergic interneurons have smooth dendrites with no or only few dendritic spines, but certain types of spiny GABAergic interneurons do actually contain substantial numbers of spines. The explanation for such spines has so far been purely structural: They increase the dendritic surface area and thus provide the ...
Scheuss, V., Bonhoeffer, T.
openaire   +3 more sources

Whole-brain mapping of long-range inputs to the VIP-expressing inhibitory neurons in the primary motor cortex

open access: yesFrontiers in Neural Circuits, 2023
The primary motor cortex (MOp) is an important site for motor skill learning. Interestingly, neurons in MOp possess reward-related activity, presumably to facilitate reward-based motor learning.
Candice Lee   +7 more
doaj   +1 more source

The development and evolution of inhibitory neurons in primate cerebrum [PDF]

open access: yesNature, 2022
AbstractNeuroanatomists have long speculated that expanded primate brains contain an increased morphological diversity of inhibitory neurons (INs)1, and recent studies have identified primate-specific neuronal populations at the molecular level2. However, we know little about the developmental mechanisms that specify evolutionarily novel cell types in ...
Matthew T. Schmitz   +8 more
openaire   +3 more sources

The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina

open access: yesCell Reports, 2019
Summary: The canonical cortical microcircuit has principally been defined by interlaminar excitatory connections among the six layers of the neocortex.
Jaclyn Ellen Frandolig   +7 more
doaj   +1 more source

Enriched expression of NF1 in inhibitory neurons in both mouse and human brain

open access: yesMolecular Brain, 2019
Neurofibromatosis type 1 (NF1) is an autosomal dominant disease caused by loss-of-function mutations in NF1 gene, which encodes a GTPase activating protein for RAS.
Hyun-Hee Ryu   +4 more
doaj   +1 more source

3D Clustering of GABAergic Neurons Enhances Inhibitory Actions on Excitatory Neurons in the Mouse Visual Cortex

open access: yesCell Reports, 2014
Summary: Neocortical neurons with similar functional properties assemble into spatially coherent circuits, but it remains unclear how inhibitory interneurons are organized. We applied in vivo two-photon functional Ca2+ imaging and whole-cell recording of
Teppei Ebina   +9 more
doaj   +1 more source

Muscarinic Acetylcholine Receptor Localization on Distinct Excitatory and Inhibitory Neurons Within the ACC and LPFC of the Rhesus Monkey

open access: yesFrontiers in Neural Circuits, 2022
Acetylcholine (ACh) can act on pre- and post-synaptic muscarinic receptors (mAChR) in the cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the prefrontal cortex—the lateral prefrontal cortex (LPFC) and the ...
Alexandra Tsolias   +2 more
doaj   +1 more source

Spatio-Temporal Sequential Memory Model With Mini-Column Neural Network

open access: yesFrontiers in Neuroscience, 2021
Memory is an intricate process involving various faculties of the brain and is a central component in human cognition. However, the exact mechanism that brings about memory in our brain remains elusive and the performance of the existing memory models is
Yawen Lan   +3 more
doaj   +1 more source

Frequency Control in Synchronized Networks of Inhibitory Neurons

open access: yesJournal of Computational Neuroscience, 1998
We analyze the control of frequency for a synchronized inhibitory neuronal network. The analysis is done for a reduced membrane model with a biophysically-based synaptic influence. We argue that such a reduced model can quantitatively capture the frequency behavior of a larger class of neuronal models.
Carson C. Chow   +3 more
openaire   +3 more sources

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