Results 11 to 20 of about 428,396 (292)
Functional Diversity of Glycinergic Commissural Inhibitory Neurons in Larval Zebrafish
Summary: Commissural inhibitory neurons in the spinal cord of aquatic vertebrates coordinate left-right body alternation during swimming. Their developmental origin, however, has been elusive.
Chie Satou +6 more
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Dravet syndrome (DS) is an intractable form of childhood epilepsy that occurs in infancy. More than 80% of all patients have a heterozygous abnormality in the SCN1A gene, which encodes a subunit of Na+ channels in the brain.
Kouya Uchino +10 more
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Background Spinal GABAergic neurons act as a critical modulator in sensory transmission like pain or itch. The monosynaptic or polysynaptic primary afferent inputs onto GABAergic neurons, along with other interneurons or projection neurons make up the ...
Peng Liu +5 more
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Exciting Information for Inhibitory Neurons [PDF]
One unsolved issue in brain development is how interneurons migrating tangentially into the cortex acquire their regional addresses and laminar positions. The study by Lodato et al. in this issue shows that projection neurons regulate the laminar fates of cortical interneurons.
Li, Guangnan, Pleasure, Samuel J.
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The firing patterns of neuronal populations often exhibit emergent collective oscillations, which can display substantial regularity even though the dynamics of individual elements is very stochastic.
David Ristič, Marko Gosak, Marko Gosak
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Inhibitory Interactions between Perigeniculate GABAergic Neurons [PDF]
Perigeniculate neurons form an interactive sheet of cells that inhibit one another as well as thalamocortical neurons in the dorsal lateral geniculate nucleus (LGNd). The inhibitory influence of the GABAergic neurons of the perigeniculate nucleus (PGN) onto other PGN neurons was examined with intracellular recordingsin vitro.
M V, Sanchez-Vives +2 more
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The recurrent network composed of excitatory and inhibitory neurons is fundamental to neocortical function. Inhibitory neurons in the mammalian neocortex are molecularly diverse, and individual cell types play unique functional roles in the neocortical ...
Jaerin Sohn +7 more
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Beyond the γ-aminobutyric acid hypothesis of schizophrenia
Abnormalities in the γ-aminobutyric acid (GABA) system have been reported in the postmortem brains of individuals with schizophrenia. In particular, the reduction of one of the GABA-synthesizing enzymes, the 67-kDa isoform of glutamate decarboxylase ...
Kazuyuki Fujihara, Kazuyuki Fujihara
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Competition through selective inhibitory synchrony [PDF]
Models of cortical neuronal circuits commonly depend on inhibitory feedback to control gain, provide signal normalization, and to selectively amplify signals using winner-take-all (WTA) dynamics.
Douglas, Rodney J. +2 more
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Inhibitory Neurons Hear Themselves during Development [PDF]
Miniature synaptic events, resulting from spontaneous presynaptic release of neurotransmitter in the absence of an action potential, are often used to assay neural connectivity and are thought to play a pivotal role in the development and maintenance of neuronal circuits. In this issue of Neuron, Trigo et al.
Owen, Scott F., Tsien, Richard W.
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