Inhibitory control of hippocampal inhibitory neurons [PDF]
Information processing within neuronal networks is determined by a dynamic partnership between principal neurons and local circuit inhibitory interneurons.
Simon eChamberland, Lisa eTopolnik
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Implications of Extended Inhibitory Neuron Development [PDF]
A prolonged developmental timeline for GABA (γ-aminobutyric acid)-expressing inhibitory neurons (GABAergic interneurons) is an amplified trait in larger, gyrencephalic animals. In several species, the generation, migration, and maturation of interneurons take place over several months, in some cases persisting after birth.
Kim, Jae-Yeon, Paredes, Mercedes F
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Exciting Information for Inhibitory Neurons [PDF]
One unsolved issue in brain development is how interneurons migrating tangentially into the cortex acquire their regional addresses and laminar positions. The study by Lodato et al. in this issue shows that projection neurons regulate the laminar fates of cortical interneurons.
Li, Guangnan, Pleasure, Samuel J.
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Building thalamic neuronal networks during mouse development
The thalamic nuclear complex contains excitatory projection neurons and inhibitory local neurons, the two cell types driving the main circuits in sensory nuclei.
Irene Huerga-Gómez +2 more
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Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro [PDF]
1. The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from anin vitro slice preparation.
Howe, James R. +2 more
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The recurrent network composed of excitatory and inhibitory neurons is fundamental to neocortical function. Inhibitory neurons in the mammalian neocortex are molecularly diverse, and individual cell types play unique functional roles in the neocortical ...
Jaerin Sohn +7 more
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Medial Superior Olivary Neurons Receive Surprisingly Few Excitatory and Inhibitory Inputs with Balanced Strength and Short-Term Dynamics [PDF]
Neurons in the medial superior olive (MSO) process microsecond interaural time differences, the major cue for localizing low-frequency sounds, by comparing the relative arrival time of binaural, glutamatergic excitatory inputs. This coincidence detection
Benedikt Grothe +5 more
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Resonant Synchronization in Heterogeneous Networks of Inhibitory Neurons [PDF]
Brain rhythms arise through the synchronization of neurons and their entrainment in a regular firing pattern. In this process, networks of reciprocally connected inhibitory neurons are often involved, but what mechanism determines the oscillation frequency is not completely understood.
Maex, Reinoud, De Schutter, Erik
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Beyond the γ-aminobutyric acid hypothesis of schizophrenia
Abnormalities in the γ-aminobutyric acid (GABA) system have been reported in the postmortem brains of individuals with schizophrenia. In particular, the reduction of one of the GABA-synthesizing enzymes, the 67-kDa isoform of glutamate decarboxylase ...
Kazuyuki Fujihara, Kazuyuki Fujihara
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The Mammalian Interaural Time Difference Detection Circuit Is Differentially Controlled by GABAB Receptors during Development [PDF]
Throughout development GABAB receptors (GABABRs) are widely expressed in the mammalian brain. In mature auditory brainstem neurons, GABABRs are involved in the short-term regulation of the strength and dynamics of excitatory and inhibitory inputs, thus ...
Grothe, Benedikt +5 more
core +1 more source

