Results 161 to 170 of about 105,210 (313)

Nobiletin Ameliorates Aβ1–42‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1

Food Safety and Health, EarlyView.
Nobiletin (NOB) ameliorates Aβ‐induced Alzheimer’s pathology by restoring circadian rhythm via Bmal1. NOB rescues cognitive deficits, synaptic damage, and mitochondrial dysfunction in mice and neurons by enhancing Bmal1/Clock oscillations and downstream mitochondrial integrity, positioning circadian regulation as a therapeutic target for Alzheimer's ...
Huajing Gao, Qinglin Qu, Ning Wang, Xue Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan   +9 more
wiley   +1 more source

Y₂‐receptor‐mediated selective inhibition of slow, inhibitory postsynaptic potential in submucous neurones of guinea‐pig caecum [PDF]

, 1994
Shauna M. C. Cunningham, S. Mihara, G.M. Lees   +2 more
openalex   +1 more source

Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot‐Marie‐Tooth 2J

Glia, EarlyView.
Hemizygous P0T124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in P0T124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS) inhibitor ...
Dennis Klein, Neslim Ercan, Xidi Yuan, Ghjuvan' Ghjacumu Shackleford, Anke Claessens, M. Laura Feltri, Lawrence Wrabetz, Maurizio D'Antonio, Rudolf Martini   +8 more
wiley   +1 more source

Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance. [PDF]

Elife
Chen X, Pan D, Liu JJ, Yang Y.
europepmc   +1 more source

Low ethanol concentrations enhance GABAergic inhibitory postsynaptic potentials in hippocampal pyramidal neurons only after block of GABAB receptors. [PDF]

, 1996
Fang Wan, Fulvia Berton, Samuel G. Madamba, Walter Francesconi, George R. Siggins   +4 more
openalex   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Incremental self-organization of spatio-temporal spike pattern detection. [PDF]

Sci Rep
Dehghani Habibabadi M, Müller L, Pawelzik K.   +2 more
europepmc   +1 more source

Mapping of excitatory and inhibitory postsynaptic potentials of neuronal populations in hippocampal slices using the GEVI, ArcLight [PDF]

, 2018
Ryuichi Nakajima, Bradley J. Baker
openalex   +1 more source

Multi‐defect‐engineering in ZnO/GO heterostructures for optoelectronic synaptic devices with ultra‐high dynamic range and low energy consumption

InfoMat, EarlyView.
A multi‐defect‐engineered ZnO/GO flat‐band heterojunction enables a high‐dynamic‐range, low‐power optoelectronic synapse through enhanced photoresponse and reduced dark current. The device achieves a record 74.9 dB dynamic range and ultralow energy consumption of 23 fJ per spike at 1 mV.
Zhiyao Zheng, Baoshi Qiao, Zhanpo Han, Jie Qiu, Yifan Yao, Chang Shu, Yajing Liu, Huan Hu, Yang Xu, Bin Yu, Dongbo Wang, Ming Wang, Zheng Li   +12 more
wiley   +1 more source

The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex. [PDF]

Nat Neurosci
Bodor AL, Schneider-Mizell CM, Zhang C, Elabbady L, Mallen A, Bergeson A, Brittain D, Buchanan J, Bumbarger DJ, Dalley R, Gamlin C, Joyce E, Kapner D, Kinn S, Mahalingam G, Seshamani S, Suckow S, Takeno M, Torres R, Yin W, Bae JA, Castro MA, Dorkenwald S, Halageri A, Jia Z, Jordan C, Kemnitz N, Lee K, Li K, Lu R, Macrina T, Mitchell E, Mondal SS, Mu S, Nehoran B, Popovych S, Silversmith W, Turner NL, Yu SC, Wong W, Wu J, Celii B, Campagnola L, Seeman SC, Jarsky T, Ren N, Arkhipov A, Reimer J, Seung HS, Reid RC, Collman F, da Costa NM.   +51 more
europepmc   +1 more source