Results 161 to 170 of about 92,954 (316)

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou   +6 more
wiley   +1 more source

Corticospinal Tract Development, Evolution, and Skilled Movements

open access: yesMovement Disorders, EarlyView.
Abstract The evolution of the corticospinal tract (CST) is closely linked to the development of skilled voluntary movements in mammals. The main evolutionary divergence concerns the position of the CST within the spinal cord white matter and its postsynaptic targets in the grey matter.
Emmanuel Roze   +2 more
wiley   +1 more source

Paired Deep Brain Stimuli Elicit Short‐Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural responses could shed light on circuit pathophysiology and inform novel approaches to neuromodulation therapies.
Sarah Brinkerhoff   +7 more
wiley   +1 more source

Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

open access: yesMovement Disorders, EarlyView.
Abstract Background The efficacy and adverse events (AEs) of bilateral magnetic resonance‐guided focused ultrasound (MRgFUS) thalamotomies for essential tremor (ET) have not been compared to those of deep brain stimulation (DBS). Furthermore, it is uncertain whether second‐side thalamotomies can be positioned differently from the first without ...
Can Sarica   +24 more
wiley   +1 more source

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