Fast and slow inhibitory postsynaptic potentials in the piriform cortex neurons.
Kensaku MORI +2 more
openaire +2 more sources
An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda +6 more
wiley +1 more source
Selective vulnerability of human synapses to soluble tau oligomers. [PDF]
Kadamangudi S +4 more
europepmc +1 more source
Molecular continuity between axon guidance and synaptic function. [PDF]
Kim S, Cho HJ, Wang IH, Park SJ.
europepmc +1 more source
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari +10 more
wiley +1 more source
Presynaptic chloride-dependent regulation of spontaneous glutamate release in the rat medial preoptic nucleus. [PDF]
Pérez-Del-Pozo M +3 more
europepmc +1 more source
Psilocybin as a novel treatment for chronic pain
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey +3 more
wiley +1 more source
Multiplexed changes in synaptic transmission underlie stress-induced reduction of persistent firing in the parietal cortex. [PDF]
Proddutur A +4 more
europepmc +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
3-Nitrotyrosine activates excitatory interneurons by inhibiting GABA receptors in the rat spinal dorsal horn. [PDF]
Kaimochi Y +9 more
europepmc +1 more source

