Results 201 to 210 of about 107,392 (304)

Decoding the mechanisms of amyloid-β in synaptic toxicity. [PDF]

J Alzheimers Dis
Toruński P, Pizzirusso G, Winblad B, Arroyo-García LE.   +3 more
europepmc   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Brain networking pain and anxiety: From basic mechanism to future treatment. [PDF]

Mol Pain
Zhuo M.
europepmc   +1 more source

Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy

The FEBS Journal, EarlyView.
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck, Lukas David Landegger   +1 more
wiley   +1 more source

Sparsification and decorrelation of granule cell activity in the dentate gyrus by noradrenaline. [PDF]

Commun Biol
Glovaci I, Mihály A, Vervaeke K, Hu H.
europepmc   +1 more source

Fast and slow inhibitory postsynaptic potentials in the piriform cortex neurons.

Proceedings of the Japan Academy, Series B, 1978
Kensaku MORI, Masahiko SATOU, Sadayuki F. TAKAGI   +2 more
openaire   +2 more sources

Refined Division of Sleep Stages in the Mouse Based on Distributed Deep Electrodes and Underlying Infra‐Slow Oscillation

Journal of Sleep Research, EarlyView.
ABSTRACT The mouse sleep is mostly recorded with only epidural electrodes and divided simply into NREM and REM stages. With the help of distributed intracerebral triplet electrodes, we searched for possible new electrophysiological signatures to characterise more specific sleep substages within the timeframe of seconds to tens of minutes.
Nanxiang Jin, Sara Häkli, Keerthana Malathi, Hennariikka Koivisto, Theodor Boc, Jonas Schimmel, Eric Castell‐Caubet, Irina Gureviciene, Heikki Tanila   +8 more
wiley   +1 more source

Propofol regulates arousal by enhancing inhibitory synaptic transmission of noradrenergic neurons in the locus coeruleus of adult male mice. [PDF]

Sci Rep
Abe T, Kurabe M, Nakamura Y, Sasaki M, Seino Y, Furutani K, Ueno M, Baba H.   +7 more
europepmc   +1 more source

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

Psychiatry and Clinical Neurosciences, EarlyView.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source

Evolutionary neuroeconomic adaptations of fast-spiking neurons in the human neocortex. [PDF]

Front Synaptic Neurosci
Szegedi V, Douida A, Hutóczki G, Novák L, Lamsa K.   +4 more
europepmc   +1 more source