Results 261 to 270 of about 276,610 (317)

Robust biodegradable synapse with sub-biological energy and extended memory for intelligent reflexive system. [PDF]

open access: yesNat Commun
Chang Y   +10 more
europepmc   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

open access: yesCell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin   +6 more
wiley   +1 more source

The emergence of electrical activity in human brain organoids. [PDF]

open access: yesStem Cell Reports
Mancinelli S, Bariselli S, Lodato S.
europepmc   +1 more source

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman   +4 more
wiley   +1 more source

Absence seizures and sleep–wake abnormalities in a rat model of GRIN2B neurodevelopmental disorder

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic mutations in GRIN2B are an important cause of severe neurodevelopmental disorders resulting in epilepsy, autism, and intellectual disability. GRIN2B encodes the GluN2B subunit of N‐methyl‐d‐aspartate receptors (NMDARs), which are ionotropic glutamate receptors critical for normal development of the nervous system and ...
Katerina Hristova   +12 more
wiley   +1 more source

Gephyrin filaments represent the molecular basis of inhibitory postsynaptic densities. [PDF]

open access: yesNat Commun
Macha A   +8 more
europepmc   +1 more source

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