Results 81 to 90 of about 14,844 (251)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Least squares contour alignment

open access: yes, 2009
The contour alignment problem, considered in this paper, is to compute the minimal distance in a least squares sense, between two explicitly represented contours, specified by corresponding points, after arbitrary rotation, scaling, and translation of ...
Markovsky, Ivan, Mahmoodi, Sasan
core  

Sequencing reads per colony before and after initial processing and after alignment based filtering.

open access: yes, 2020
Sequencing reads per colony before and after initial processing and after alignment based filtering.
Pnina Cohen (6753437)   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Application of the Adaptive Mixed-Order Cubature Particle Filter Algorithm Based on Matrix Lie Group Representation for the Initial Alignment of SINS

open access: yesInformation
Under large azimuth misalignment conditions, the initial alignment of strapdown inertial navigation systems (SINS) is challenged by the nonlinear characteristics of the error model.
Ning Wang, Fanming Liu
doaj   +1 more source

Ontology Alignment Evaluation Initiative: Six Years of Experience [PDF]

open access: yes, 2011
In the area of semantic technologies, benchmarking and systematic evaluation is not yet as established as in other areas of computer science, e.g., information retrieval. In spite of successful attempts, more effort and experience are required in order to achieve such a level of maturity.
Euzenat, Jérôme   +4 more
openaire   +4 more sources

MLCA—A Machine Learning Framework for INS Coarse Alignment

open access: yesSensors, 2020
Inertial navigation systems provides the platform’s position, velocity, and attitude during its operation. As a dead-reckoning system, it requires initial conditions to calculate the navigation solution.
Idan Zak, Reuven Katz, Itzik Klein
doaj   +1 more source

Alignment method of off-axis RC reflective optical system

open access: yes, 2016
Off-axis optical system has a wide application in space optics and remote detective area. The high surface shape accuracy can be ensured with the development of advanced manufacture technique.
Hou Xiao-hua   +4 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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