Results 261 to 270 of about 71,189 (303)
Some of the next articles are maybe not open access.
Initiation of DNA replication in human chromosomes
Experimental Cell Research, 1977Abstract DNA replication within the first 10 min of the S phase was studied using synchronized human diploid cells. It appeared that every chromosome in the human genome, including late-replicating X, had segment(s) which initiated DNA replication within the first 10 min of the S phase.
openaire +2 more sources
Initiation of DNA replication in yeast chromosomes
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1987Abstract A family of DNA fragments from the yeast genome has properties that suggest that chromosome replication starts at specific DNA sequences. These elements (autonomously replicating sequences: ARS) have a bipartite structure: a small (less than 20 base pairs) AT-rich region essential for function, flanked by larger regions ...
openaire +2 more sources
Initiation of DNA replication in eukaryotic chromosomes
Journal of Cellular Biochemistry, 1998Our understanding of the process by which eukaryotes regulate initiation of DNA replication has made remarkable advances in the past few years, thanks in large part to the explosion of genetic and biochemical information on the budding yeast, Saccharomyces cerevisiae.
openaire +3 more sources
Initiation and Termination of Chromosome Replication
2014In this chapter, emphasis is on the processes of initiation and termination of replication of the B. subtilis chromosome. As an introduction to the discussion of these topics, a brief account is given of the work that has afforded a general picture of the topology of the B. subtilis chromosome through the three phases of the replication cycle.
H. Yoshikawa, R. G. Wake
openaire +1 more source
Analysis of the temporal program of replication initiation in yeast chromosomes
Journal of Cell Science, 1995ABSTRACT The multiple origins of eukaryotic chromosomes vary in the time of their initiation during S phase. In the chromosomes of Saccharomyces cerevisiae the presence of a functional telomere causes nearby origins to delay initiation until the second half of S phase. The key feature of telomeres that causes the replication delay is the
K L, Friedman +3 more
openaire +2 more sources
Initiation at Closely Spaced Replication Origins in a Yeast Chromosome
Science, 1993Replication of eukaryotic chromosomes involves initiation at origins spaced an average of 50 to 100 kilobase pairs. In yeast, potential origins can be recognized as autonomous replication sequences (ARSs) that allow maintenance of plasmids. However, there are more ARS elements than active chromosomal origins.
B J, Brewer, W L, Fangman
openaire +2 more sources
Initiation of DNA replication in eukaryotic chromosomes
Trends in Biochemical Sciences, 1981Abstract The large amount of DNA in eukaryotic chromosomes is duplicated exactly for distribution to daughter cells at division. Unlike prokaryotes, the eukaryote must co-ordinate multiple initiations of replication on a single molecule so as to replicate the DNA once, and only once, in a cell cycle.
openaire +1 more source
Regulation of Initiation ofBacillus subtilisChromosome Replication
Plasmid, 1999Bacterial chromosome replication is tightly regulated at the initiation stage to coordinate with mass increase. Together with chromosome partition at cell division, this regulation mechanism ensures the proper number of chromosomes in daughter cells at any growth rate.
S, Moriya +3 more
openaire +2 more sources
A new mutant of Bacillus subtilis altered in the initiation of chromosome replication
Molecular and General Genetics MGG, 1975We have isolated a new mutant of Bacillus subtilis temperature sensitive in DNA replication; its properties are those of an initiation mutant. When liquid cultures are shifted to 48 degrees DNA replication is the first macromolecular synthesis that stops, but only after synthesis of the amount of DNA predicted for the completion of one replication ...
S. RIVA +6 more
openaire +3 more sources
Coupling the initiation of chromosome replication to cell size in Escherichia coli
Current Opinion in Microbiology, 2003Bacterial cells change size dramatically with change in growth rate, but the ratio between cell volume and the number of copies of the origin of chromosome replication (oriC) is roughly constant at the time of initiation of DNA replication at almost all growth rates.
William D, Donachie, Garry W, Blakely
openaire +2 more sources