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Expression of functional GPR35 in human iNKT cells

Biochemical and Biophysical Research Communications, 2010
The aim of this study was to examine the expression of G protein-coupled receptor (GPR)35 in human invariant natural killer T (iNKT) cells and to determine the functional effects induced by selective activation of this receptor. RT-PCR analysis showed that both human iNKT cells and resting PBMC expressed GPR35; GPR35 protein resulted mostly localized ...
FALLARINI, Silvia   +4 more
openaire   +2 more sources

CAR-iNKT cell therapy: mechanisms, advantages, and challenges

Current Research in Translational Medicine
In recent years, chimeric antigen receptor (CAR) T-cell therapy has emerged as a groundbreaking approach in cancer immunotherapy. Particularly in hematologic malignancies, such as B-cell acute lymphoblastic leukemia (B-ALL), B cell lymphomas and multiple myeloma.
Zixuan Wang, Guangji Zhang
openaire   +2 more sources

iNKT cells for allogeneic cell therapy

Cell and Gene Therapy Insights, 2023
Eleni Chantzoura, Paul Ibbett
openaire   +1 more source

High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision

Cell Reports, 2020
Carolina de Amat Herbozo   +2 more
exaly  

iNKT cell agonists as vaccine adjuvants to combat infectious diseases

Carbohydrate Research, 2022
Rui Luo, Zheng Liu
exaly  

Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

Cancer Cell, 2018
Antonia Rotolo   +2 more
exaly  

iNKT cell autoreactivity: what is 'self' and how is it recognized?

Nature Reviews Immunology, 2010
Laurent Gapin
exaly  

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