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Innate Immune Responses to Fungal Allergens

Current Allergy and Asthma Reports, 2016
In this review, we describe innate immunity to fungi and the ability of pattern recognition receptors (PRRs) to recognize fungal-associated molecular patterns (FAMPs) and danger-associated molecular patterns (DAMPs).Protective responses against fungal antigens can be divided into two parts: innate immunity and adaptive immunity.
Jay M, Portnoy   +2 more
openaire   +2 more sources

Innate Immune Responses

2010
When viruses enter the host, they are first detected by the innate immune system, which comprises cytokines, sentinel cells (dendritic cells [DCs] and macrophages), complement, and natural killer (NK) cells. A second family of pattern recognition receptors comprises the cytoplasmic sensors of viral nucleic acids, MDA-5 (melanoma differentiation ...
openaire   +1 more source

Modulation of Innate Immune Responses by Hantaviruses

Critical Reviews™ in Immunology, 2010
Hantavirus infection can cause hantavirus cardiopulmonary syndrome or hemorrhagic fever with renal syndrome depending on the virus species involved. The determinants for the virus species specific virulence in humans are unclear. Successful infection is a conditio sine qua non for the virulence of a virus and it is well-known that the innate interferon
openaire   +2 more sources

Regulation of innate immune responses in the brain

Nature Reviews Immunology, 2009
Microglial cells are the main innate immune cells of the complex cellular structure of the brain. These cells respond quickly to pathogens and injury, accumulate in regions of degeneration and produce a wide variety of pro-inflammatory molecules. These observations have resulted in active debate regarding the exact role of microglial cells in the brain
openaire   +2 more sources

Innate and adaptive immune responses in asthma

Nature Medicine, 2012
The recognition that asthma is primarily an inflammatory disorder of the airways associated with T helper type 2 (T(H)2) cell-dependent promotion of IgE production and recruitment of mast cells and eosinophils has provided the rationale for disease control using inhaled corticosteroids and other anti-inflammatory drugs.
openaire   +2 more sources

Stress response to innate immune signalosomes

Nature Reviews Immunology, 2019
Cytosolic protein oligomers formed by certain innate immune receptors and their adaptor proteins trigger the integrated stress response pathway, which regulates the stability of these signalosomes as well as downstream inflammatory responses.
openaire   +2 more sources

The Innate Immune Response toMycobacterium tuberculosisInfection

Annual Review of Immunology, 2021
Sarah Stanley, Erik Van Dis
exaly  

The Innate Immune Response

2023
Beatrix Fahnert, Phoebe Lostroh
openaire   +1 more source

Phase separation in innate immune response and inflammation-related diseases

Frontiers in Immunology, 2023
Ming Shi, Cao Jingyan
exaly  

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