Results 1 to 10 of about 728,146 (346)
CNS remyelination and the innate immune system [PDF]
Frontiers in Cell and Developmental Biology, 2016 A misguided inflammatory response is frequently implicated in myelin damage. Particularly prominent among myelin diseases, multiple sclerosis (MS) is an autoimmune condition, with immune–mediated damage central to its aetiology.
Christopher E McMurran +3 more
doaj +8 more sources
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
Mediators of Inflammation, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj +5 more sources
Microorganisms, 2021 Vibrosis is one of the major threats in aquaculture farming, and due to the increasing antimicrobial resistance of different Vibrio species, there is an urgent need to replace conventional treatments with more sustainable solutions.
Barbara Rossi +6 more
doaj +1 more source
Innate Immune Responses to Influenza Virus Infections in the Upper Respiratory Tract
Viruses, 2021 The innate immune system is the host’s first line of immune defence against any invading pathogen. To establish an infection in a human host the influenza virus must replicate in epithelial cells of the upper respiratory tract. However, there are several
Edin J. Mifsud, Miku Kuba, Ian G. Barr
doaj +1 more source
Innate immune sensors for detecting nucleic acids during infection
Journal of Laboratory Medicine, 2022 Innate immune receptors detect nucleic acids, such as viruses, and initiate an immune response by secreting interferon (IFN) and regulating IFN-stimulated genes (ISG).
Ghoreshi Zohreh-alsadat +4 more
doaj +1 more source
Engineering physical microenvironments to study innate immune cell biophysics
APL Bioengineering, 2022 Innate immunity forms the core of the human body's defense system against infection, injury, and foreign objects. It aims to maintain homeostasis by promoting inflammation and then initiating tissue repair, but it can also lead to disease when ...
Nikita Kalashnikov, Christopher Moraes
doaj +1 more source
Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]
, 2020 The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia +4 more
core +2 more sources
Boletim do Instituto de Pesca, 2019 Linking proprieties of adhesion, infectious capacities and antibiotic resistance of pathogen bacteria could help to treat fish diseases. Adhesions of ten fish pathogenic bacteria were tested in microtiter plates vacant, coated with skin or gut mucus ...
Said Ben Hamed +5 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2021 Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed +17 more
doaj +1 more source
Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
, 2016 Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core +1 more source