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Function of immune cells and effector molecules of the innate immune system in the establishment and maintenance of pregnancy in mammals — A review [PDF]

Animal Bioscience
In mammalian species, pregnancy is a complex process that involves the maternal recognition of pregnancy, implantation, decidualization, placentation, and parturition.
Soohyung Lee, Inkyu Yoo, Yugyeong Cheon, Eunhyeok Choi, Seonghyun Kim, Hakhyun Ka   +5 more
doaj   +2 more sources

Antimicrobial Power of Organic Acids and Nature-Identical Compounds against Two Vibrio spp.: An In Vitro Study

Microorganisms, 2021
Vibrosis is one of the major threats in aquaculture farming, and due to the increasing antimicrobial resistance of different Vibrio species, there is an urgent need to replace conventional treatments with more sustainable solutions.
Barbara Rossi, Maria Angéles Esteban, José María García-Beltran, Giulia Giovagnoni, Alberto Cuesta, Andrea Piva, Ester Grilli   +6 more
doaj   +1 more source

Innate Immune Responses to Influenza Virus Infections in the Upper Respiratory Tract

Viruses, 2021
The innate immune system is the host’s first line of immune defence against any invading pathogen. To establish an infection in a human host the influenza virus must replicate in epithelial cells of the upper respiratory tract. However, there are several
Edin J. Mifsud, Miku Kuba, Ian G. Barr
doaj   +1 more source

Innate immune sensors for detecting nucleic acids during infection

Journal of Laboratory Medicine, 2022
Innate immune receptors detect nucleic acids, such as viruses, and initiate an immune response by secreting interferon (IFN) and regulating IFN-stimulated genes (ISG).
Ghoreshi Zohreh-alsadat, Nakhaee Mohsen, Samie Mohammad, Zak Mohsen Sharif, Arefinia Nasir   +4 more
doaj   +1 more source

Engineering physical microenvironments to study innate immune cell biophysics

APL Bioengineering, 2022
Innate immunity forms the core of the human body's defense system against infection, injury, and foreign objects. It aims to maintain homeostasis by promoting inflammation and then initiating tissue repair, but it can also lead to disease when ...
Nikita Kalashnikov, Christopher Moraes
doaj   +1 more source

Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?

Frontiers in Aging Neuroscience, 2021
Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed, Md. Mahiuddin Ahmed, Md. Mahiuddin Ahmed, Noah R. Johnson, Noah R. Johnson, Noah R. Johnson, Timothy D. Boyd, Timothy D. Boyd, Timothy D. Boyd, Christina Coughlan, Christina Coughlan, Christina Coughlan, Heidi J. Chial, Heidi J. Chial, Heidi J. Chial, Huntington Potter, Huntington Potter, Huntington Potter   +17 more
doaj   +1 more source

Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream

BMC Genomics, 2017
Background Skin and its mucus are known to be the first barrier of defence against any external stressors. In fish, skin wounds frequently appear as a result of intensive culture and also some diseases have skin ulcers as external clinical signs. However,
Héctor Cordero, Monica F. Brinchmann, Alberto Cuesta, María A. Esteban   +3 more
doaj   +1 more source

Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion

Frontiers in Microbiology, 2021
Hepatitis viruses are primary causative agents of hepatitis and represent a major source of public health problems in the world. The host innate immune system forms the first line of defense against hepatitis viruses.
Chonghui Xu, Chonghui Xu, Jizheng Chen, Jizheng Chen, Xinwen Chen, Xinwen Chen   +5 more
doaj   +1 more source

Mercury and its toxic effects on fish

AIMS Environmental Science, 2017
Mercury (Hg) and its derivative compounds have been parts of widespread pollutants of the aquatic environment. Since Hg is absorbed by fish and passed up the food chain to other fish-eating species, it does not only affect aquatic ecosystems but also ...
Patricia Morcillo, Maria Angeles Esteban, Alberto Cuesta   +2 more
doaj   +1 more source

Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

Frontiers in Immunology, 2019
Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria.
Elena Chaves-Pozo, Yulema Valero, Yulema Valero, Maria Teresa Lozano, Pablo Rodríguez-Cerezo, Liang Miao, Vittorio Campo, Maria Angeles Esteban, Alberto Cuesta   +8 more
doaj   +1 more source