Results 11 to 20 of about 12,901 (262)
Innate immune system and preeclampsia [PDF]
Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda+3 more
doaj +6 more sources
CNS remyelination and the innate immune system [PDF]
A misguided inflammatory response is frequently implicated in myelin damage. Particularly prominent among myelin diseases, multiple sclerosis (MS) is an autoimmune condition, with immune–mediated damage central to its aetiology.
Christopher E McMurran+3 more
doaj +4 more sources
Prion Disease and the Innate Immune System [PDF]
Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectious ...
Barry M. Bradford, Neil A. Mabbott
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The interaction of innate immune and adaptive immune system
The innate immune system serves as the body's first line of defense, utilizing pattern recognition receptors like Toll‐like receptors to detect pathogens and initiate rapid response mechanisms.
Ruyuan Wang+12 more
doaj +3 more sources
The Innate Immune System in Alzheimer’s Disease [PDF]
Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloid β (Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (
Allal Boutajangout, Thomas Wisniewski
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The Innate Immune System and Transplantation [PDF]
The sensitive and broadly reactive character of the innate immune system makes it liable to activation by stress factors other than infection. Thermal and metabolic stresses experienced during the transplantation procedure are sufficient to trigger the innate immune response and also augment adaptive immunity in the presence of foreign antigen on the ...
Farrar, Conrad A+2 more
openaire +4 more sources
The innate immune system 'puzzle' [PDF]
Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
openalex +3 more sources
Bone and the Innate Immune System [PDF]
The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Mary C. Nakamura+2 more
openaire +5 more sources
The innate immune system in the intestine [PDF]
The innate immune system provides the first line of host defense against invading pathogens. Innate immune responses are initiated by germline-encoded PRR, which recognize specific structures expressed by microorganisms. TLR are a family of PRR which sense a wide range of microorganisms, including bacteria, fungi, protozoa and viruses.
Kosuke Fujimoto, Satoshi Uematsu
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The innate immune system in transplantation [PDF]
The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Martin H. Oberbarnscheidt+2 more
openaire +3 more sources