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Innate immune system and preeclampsia [PDF]
Frontiers in Immunology, 2014 Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda +3 more
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Prion Disease and the Innate Immune System [PDF]
Viruses, 2012 Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectious ...
Barry M. Bradford, Neil A. Mabbott
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The Innate Immune System in Alzheimer’s Disease [PDF]
International Journal of Cell Biology, 2013 Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloid β (Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (
Allal Boutajangout, Thomas Wisniewski
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The interaction of innate immune and adaptive immune system
MedCommThe innate immune system serves as the body's first line of defense, utilizing pattern recognition receptors like Toll‐like receptors to detect pathogens and initiate rapid response mechanisms.
Ruyuan Wang +12 more
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The Innate Immune System and Transplantation [PDF]
Cold Spring Harbor Perspectives in Medicine, 2013 The sensitive and broadly reactive character of the innate immune system makes it liable to activation by stress factors other than infection. Thermal and metabolic stresses experienced during the transplantation procedure are sufficient to trigger the innate immune response and also augment adaptive immunity in the presence of foreign antigen on the ...
Farrar, Conrad A +2 more
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The innate immune system 'puzzle' [PDF]
Nature Immunology, 2006 Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
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Bone and the Innate Immune System [PDF]
Current Osteoporosis Reports, 2014 The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Mary C. Nakamura +2 more
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The innate immune system in the intestine [PDF]
Microbiology and Immunology, 2010 The innate immune system provides the first line of host defense against invading pathogens. Innate immune responses are initiated by germline-encoded PRR, which recognize specific structures expressed by microorganisms. TLR are a family of PRR which sense a wide range of microorganisms, including bacteria, fungi, protozoa and viruses.
Kosuke Fujimoto, Satoshi Uematsu
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The Chemokine System in Innate Immunity [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Chemokines are chemotactic cytokines that control the migration and positioning of immune cells in tissues and are critical for the function of the innate immune system. Chemokines control the release of innate immune cells from the bone marrow during homeostasis as well as in response to infection and inflammation.
Andrew D. Luster, Caroline L. Sokol
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Evolution of innate immune systems* [PDF]
Biochemistry and Molecular Biology Education, 2005 AbstractInnate immunity is the oldest form of defense and is found to some degree in all species. It predates the adaptive immune system, consisting of antibodies, B cells, T cells, and the major histocompatibility antigens. These are found only in higher vertebrates and have been the focus of the majority of immunological research, particularly in ...
Jakob Suckale +2 more
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