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The innate immune system in transplantation [PDF]
Seminars in Immunology, 2011 The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Martin H. Oberbarnscheidt +2 more
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Systems biology of innate immunity [PDF]
Cellular Immunology, 2006 Systems Biology has emerged as an exciting research approach in molecular biology and functional genomics that involves a systematic use of genomic, proteomic, and metabolomic technologies for the construction of network-based models of biological processes.
Roland Nilsson +4 more
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Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
, 2020 Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
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Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream
BMC Genomics, 2017 Background Skin and its mucus are known to be the first barrier of defence against any external stressors. In fish, skin wounds frequently appear as a result of intensive culture and also some diseases have skin ulcers as external clinical signs. However,
Héctor Cordero +3 more
doaj +1 more source
Neuro-immune communication in C. elegans defense against pathogen infection
Current Research in Immunology, 2021 The innate immune system is a complex collection of physical barriers and physiological defense responses to internal and external environmental assaults. Recent studies in the model organism Caenorhabditis elegans have highlighted how the nervous system
Phillip Wibisono, Jingru Sun
doaj +1 more source
libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
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Mercury and its toxic effects on fish
AIMS Environmental Science, 2017 Mercury (Hg) and its derivative compounds have been parts of widespread pollutants of the aquatic environment. Since Hg is absorbed by fish and passed up the food chain to other fish-eating species, it does not only affect aquatic ecosystems but also ...
Patricia Morcillo +2 more
doaj +1 more source
Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion
Frontiers in Microbiology, 2021 Hepatitis viruses are primary causative agents of hepatitis and represent a major source of public health problems in the world. The host innate immune system forms the first line of defense against hepatitis viruses.
Chonghui Xu +5 more
doaj +1 more source
Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity
Frontiers in Immunology, 2019 Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria.
Elena Chaves-Pozo +8 more
doaj +1 more source
'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources