Results 21 to 30 of about 1,613,203 (345)
Frontiers in Aging Neuroscience, 2021 Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed +17 more
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Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
, 2016 Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
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Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity
Frontiers in Immunology, 2019 Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria.
Elena Chaves-Pozo +8 more
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Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion
Frontiers in Microbiology, 2021 Hepatitis viruses are primary causative agents of hepatitis and represent a major source of public health problems in the world. The host innate immune system forms the first line of defense against hepatitis viruses.
Chonghui Xu +5 more
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libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
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The Role of the Immune System in the Pathophysiology of Essential Hypertension
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022 Hypertension (HTN) is a critical worldwide health issue and an imperative risk factor for the development of cardiovascular disease and kidney disease. There are many crevices in our knowledge about the pathophysiology of HTN.
Mahsa Rekabi +7 more
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'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
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Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]
, 2020 The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia +4 more
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Fish Peroxiredoxins and Their Role in Immunity
Biology, 2015 Peroxiredoxins (Prxs) are a family of antioxidant enzymes that protect cells from oxidative damage. In addition, Prxs may act as modulators of inflammation, protect against cell death and tumour progression, and facilitate tissue repair after damage. The
Yulema Valero +4 more
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The Evasion of Antiviral Innate Immunity by Chicken DNA Viruses
Frontiers in Microbiology, 2021 The innate immune system constitutes the first line of host defense. Viruses have evolved multiple mechanisms to escape host immune surveillance, which has been explored extensively for human DNA viruses. There is growing evidence showing the interaction
Li Gao, Shijun Zheng, Yongqiang Wang
doaj +1 more source