Results 21 to 30 of about 1,083,097 (291)
Frontiers in Immunology, 2019 The immune system is composed of two subsystems—the innate immune system and the adaptive immune system. The innate immune system is the first to respond to pathogens and does not retain memory of previous responses.
Nicole C. Smith +2 more
doaj +1 more source
libtissue - implementing innate immunity [PDF]
499-506, Proceedings of the IEEE Congress on Evolutionary
Computation (CEC2006), Vancouver, Canada, 2006, 2010 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems. A number of key general properties observed in the biological innate and adaptive immune systems were hughlighted, and how such properties might be ...
arxiv +1 more source
Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
Frontiers in Cardiovascular Medicine, 2015 The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
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Understanding Human Innate Immune System Dependencies using Graph Neural Networks [PDF]
arXiv, 2021 Since the rapid outbreak of Covid-19 and with no approved vaccines to date, profound research interest has emerged to understand the innate immune response to viruses. This understanding can help to inhibit virus replication, prolong adaptive immune response, accelerated virus clearance, and tissue recovery, a key milestone to propose a vaccine to ...
arxiv
Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges
Frontiers in Immunology, 2017 The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
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Virulence, 2021 Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan +4 more
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Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation
Mediators of Inflammation, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj +1 more source
Exploring The Contribution of Innate Immune Cells to Breast Cancer Immunotherapy [PDF]
arXiv, 2023 Breast cancer is the leading type of cancer in women. About 10-15% of breast cancers are triple-negative breast cancer (TNBC), a subtype with the worst prognosis. Due to the lack of estrogen, progesterone and HER2 receptor expression, chemotherapies have been the standard of care for decades.
arxiv
Planarians (Platyhelminthes)—An Emerging Model Organism for Investigating Innate Immune Mechanisms
Frontiers in Cellular and Infection Microbiology, 2021 An organism responds to the invading pathogens such as bacteria, viruses, protozoans, and fungi by engaging innate and adaptive immune system, which functions by activating various signal transduction pathways. As invertebrate organisms (such as sponges,
Luis Johnson Kangale +9 more
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source