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Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System [PDF]
Vaccines, 2018 Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted scientists in utilizing them as a unique tool in various applications in
Mona O Mohsen +2 more
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COVID-19 and the human innate immune system
Cell, 2021 The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the human population represents a tremendous medical and economic crisis.
Joachim L Schultze, Anna C Aschenbrenner
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Innate Immune System Cells in Atherosclerosis
Archives of Medical Research, 2014Atherosclerosis is a chronic inflammatory disease of the arterial wall characterized by innate and adaptive immune system involvement. A key component of atherosclerotic plaque inflammation is the persistence of different innate immune cell types including mast cells, neutrophils, natural killer cells, monocytes, macrophages and dendritic cells ...
Luis, Chávez-Sánchez +5 more
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How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
Nature Reviews Immunology, 2021 Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in preclinical models and emerging evidence in humans have established the crucial roles of the innate and adaptive immune systems in driving atherosclerosis-associated
Payel Roy +2 more
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The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?
Cell Host and Microbe, 2020 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has had devastating global impacts and will continue to have dramatic effects on public health for years to come.
Catherine A Blish
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Innate Immunity in the Mucosal Immune System
Current Pharmaceutical Design, 2006The mucosal immune system is equipped with unique innate and acquired defense mechanisms which provide a first line of protection against ingested and inhaled infectious agents. Peyer's patches (PPs) and nasopharynx-associated lymphoid tissue (NALT) have been shown to be important inductive sites for the initiation of the acquired phase of antigen ...
Tomonori, Nochi, Hiroshi, Kiyono
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The innate immune system and cell death in autoinflammatory and autoimmune disease.
Current Opinion in Immunology, 2020The innate immune system, the first line of defense against pathogens and host tissue damage, initiates pro-inflammatory responses which, when dysregulated, promote inflammation to drive a broad range of autoimmune diseases.
David E. Place, T. Kanneganti
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Innate Immunity in Systemic Sclerosis
Current Rheumatology Reports, 2017Systemic sclerosis (SSc) is a heterogeneous autoimmune disease which has defined three hallmarks: Small vessel vasculopathy, production of autoantibodies and fibroblast dysfunction. The exact aetiology of the disease remains unknown, due to the complex nature of the cellular signalling pathways involved. However, there is strong and consistent evidence
Christopher, Dowson +3 more
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