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Innate immunity in systemic sclerosis pathogenesis

Clinical Science, 2013
The innate immune system is a critical part of the response to pathogens and overall immunity. Compared with the adaptive immune response, these innate responses are not antigen-specific and recognize patterns in bacteria, viruses and fungi. Chief among these are TLRs (Toll-like receptors).
openaire   +2 more sources

Pathogen Recognition by the Innate Immune System

International Reviews of Immunology, 2011
H. Kumar, T. Kawai, S. Akira
semanticscholar   +1 more source

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape

Nature Immunology, 2019
P. Hubel   +14 more
semanticscholar   +1 more source

The innate immune system

2010
The innate immune system comprises evolutionarily ancient mechanisms that mediate first-line responses against microbial pathogens, and are also important in priming and execution of adaptive immune responses, and in defence against tumours. These responses, which recognize microbial non-self, damaged self, and absent self, are characterized by ...
openaire   +1 more source

Peptidoglycan recognition by the innate immune system

Nature reviews. Immunology, 2018
Andrea J. Wolf, D. Underhill
semanticscholar   +1 more source

The Innate Immune System

2007
Abstract The innate immune system recognizes infectious danger and launches an immediate anti-infective response. It relies on recognition systems (receptors) that were selected during phylogeny and which in part are shared with non-vertebrate organisms.
openaire   +1 more source

Regulation of metabolism by the innate immune system

Nature Reviews Endocrinology, 2016
D. Lackey, J. Olefsky
semanticscholar   +1 more source

The Effect of Short‐Term Hyperglycemia on the Innate Immune System

American Journal of the Medical Sciences, 2016
Nagham Jafar, H. Edriss, K. Nugent
semanticscholar   +1 more source

Bacterial origins of human cell-autonomous innate immune mechanisms

Nature reviews. Immunology, 2022
Tanita Wein, R. Sorek
semanticscholar   +1 more source

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