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The immune memory of innate immune systems
International ImmunologyAbstract Immune memory has long been considered a function specific to adaptive immune systems; however, adaptive immune memory alone has not fully explained the mechanism by which vaccines exert their protective effects against nontarget pathogens.
Yasuhiro Kato, Atsushi Kumanogoh
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Neutrophils: Cinderella of innate immune system
International Immunopharmacology, 2010Neutrophils are the first line of innate immune defense against infectious diseases. However, since their discovery by Elie Metchnikoff, they have always been considered tissue-destructive cells responsible for inflammatory tissue damage occurring during acute infections.
Kumar, V., Sharma, A.
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Innate Immune System Cells in Atherosclerosis
Archives of Medical Research, 2014Atherosclerosis is a chronic inflammatory disease of the arterial wall characterized by innate and adaptive immune system involvement. A key component of atherosclerotic plaque inflammation is the persistence of different innate immune cell types including mast cells, neutrophils, natural killer cells, monocytes, macrophages and dendritic cells ...
Luis, Chávez-Sánchez +5 more
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Earthworm Innate Immune System
2010Nonself recognition is the basis of innate and adaptive immune responses and it depends on immune receptors. Caenorhabditis elegans and Drosophila animal models have added ample information to define molecular homology especially at the level of signal transduction.
Péter Engelmann +3 more
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Innate immunity in systemic sclerosis pathogenesis
Clinical Science, 2013The innate immune system is a critical part of the response to pathogens and overall immunity. Compared with the adaptive immune response, these innate responses are not antigen-specific and recognize patterns in bacteria, viruses and fungi. Chief among these are TLRs (Toll-like receptors).
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Specific memory within innate immune systems
Trends in Immunology, 2005Research into immune defense has been considerably enriched by the increasing focus on innate immunity. This type of immunity is still considered to lack specific memory, largely because there is no evidence of mechanisms that could provide such memory (such as acquired immunity).
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2007
Abstract The innate immune system recognizes infectious danger and launches an immediate anti-infective response. It relies on recognition systems (receptors) that were selected during phylogeny and which in part are shared with non-vertebrate organisms.
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Abstract The innate immune system recognizes infectious danger and launches an immediate anti-infective response. It relies on recognition systems (receptors) that were selected during phylogeny and which in part are shared with non-vertebrate organisms.
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Innate immunity in the nervous system
2009The complement (C) system plays a central role in innate immunity and bridges innate and adaptive immune responses. A fine balance of C activation and regulation mediates the elimination of invading pathogens and the protection of the host from excessive C deposition on healthy tissues.
V, Ramaglia, F, Baas
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Lipopolysaccharide delivery systems in innate immunity
Trends in ImmunologyLipopolysaccharide (LPS), a key component of the outer membrane in Gram-negative bacteria (GNB), is widely recognized for its crucial role in mammalian innate immunity and its link to mortality in intensive care units. While its recognition via the Toll-like receptor (TLR)-4 receptor on cell membranes is well established, the activation of the ...
Jiao Liu, Rui Kang, Daolin Tang
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2010
The innate immune system comprises evolutionarily ancient mechanisms that mediate first-line responses against microbial pathogens, and are also important in priming and execution of adaptive immune responses, and in defence against tumours. These responses, which recognize microbial non-self, damaged self, and absent self, are characterized by ...
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The innate immune system comprises evolutionarily ancient mechanisms that mediate first-line responses against microbial pathogens, and are also important in priming and execution of adaptive immune responses, and in defence against tumours. These responses, which recognize microbial non-self, damaged self, and absent self, are characterized by ...
openaire +1 more source