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Systems Biology and Innate Immunity
Journal of Innate Immunity, 2013 The innate immune system is the first line of host defense against invading microorganisms and is essential for maintenance of host health. The innate immune response is largely mediated by soluble host factors—such as complement—and phagocytic leukocytes.
Scott D, Kobayashi, Frank R, Deleo
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Main Components of Fish Immunity: An Overview of the Fish Immune System
Fishes, 2023 Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents
Doaa M. Mokhtar +5 more
semanticscholar +1 more source
Long‐term reprogramming of the innate immune system
Journal of Leukocyte Biology, 2018 During the last few years, a growing body of evidence has shown that immunological memory is not an exclusive trait of lymphocytes, as many inflammatory insults can alter the functionality and the responsiveness of the innate immune system in the long ...
Jorge Domínguez-Andrés, M. Netea
semanticscholar +1 more source
Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges
Frontiers in Immunology, 2017 The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
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Potential role of gut microbiota in induction and regulation of innate immune memory [PDF]
, 2019 The gut microbiota significantly regulates the development and function of the innate and adaptive immune system. The attribute of immunological memory has long been linked only with adaptive immunity.
Agrewala, Javed N +4 more
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RNA sensors of the innate immune system and their detection of pathogens
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2017 The innate immune system plays a critical role in pathogen recognition and initiation of protective immune response through the recognition of pathogen associated molecular patterns (PAMPs) by its pattern recognition receptors (PRRs).
Nanhua Chen +5 more
semanticscholar +1 more source
Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]
, 2017 Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín +1 more
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Bacteriophage and the Innate Immune System: Access and Signaling
Microorganisms, 2019 Bacteriophage and the bacteria they infect are the dominant members of the gastrointestinal microbiome. While bacteria are known to be central to maintenance of the structure, function, and health of the microbiome, it has only recently been recognized ...
A. Carroll-Portillo, Henry C. Lin
semanticscholar +1 more source
Planarians (Platyhelminthes)—An Emerging Model Organism for Investigating Innate Immune Mechanisms
Frontiers in Cellular and Infection Microbiology, 2021 An organism responds to the invading pathogens such as bacteria, viruses, protozoans, and fungi by engaging innate and adaptive immune system, which functions by activating various signal transduction pathways. As invertebrate organisms (such as sponges,
Luis Johnson Kangale +9 more
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Bone and the Innate Immune System [PDF]
Current Osteoporosis Reports, 2014 The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Charles, Julia F, Nakamura, Mary C
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