Results 51 to 60 of about 728,146 (346)

Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]

, 2017
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín, Ramos Morales, Francisco   +1 more
core   +1 more source

Planarians (Platyhelminthes)—An Emerging Model Organism for Investigating Innate Immune Mechanisms

Frontiers in Cellular and Infection Microbiology, 2021
An organism responds to the invading pathogens such as bacteria, viruses, protozoans, and fungi by engaging innate and adaptive immune system, which functions by activating various signal transduction pathways. As invertebrate organisms (such as sponges,
Luis Johnson Kangale, Luis Johnson Kangale, Didier Raoult, Didier Raoult, Didier Raoult, Pierre-Edouard Fournier, Pierre-Edouard Fournier, Prasad Abnave, Eric Ghigo, Eric Ghigo   +9 more
doaj   +1 more source

The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]

, 2020
Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C, Neri, Piergiorgio, Perez, Victor L, Periman, Laura M, Saban, Daniel R   +4 more
core   +1 more source

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

From traumatic childhood to cocaine abuse: the critical function of the immune system [PDF]

, 2018
Background: Experiencing traumatic childhood is a risk factor for developing substance use disorder (SUD), but the mechanisms that underlie this relationship have not been determined.
Aricò, Eleonora, Bussone, Silvia, Carola, Valeria, Casella, Pietro, Catale, Clarissa, Chiurchiù, Valerio, Di Sabato, Paola, D’Argenio, Alberto, Guatteo, Ezia, Lo Iacono, Luisa, Maccarrone, Mauro, Martini, Alessandro, Mercuri, Nicola B., Perrone, Fabiana, Puglisi-Allegra, Stefano, Troisi, Alfonso, Valzania, Alessandro, Viscomi, Maria Teresa   +17 more
core   +1 more source

Recombinant DnaK orally administered protects axenic European sea bass against vibriosis [PDF]

, 2020
Vibrio anguillarum causes high mortality in European sea bass (Dicentrarchus labrax) larviculture and is a hindering factor for successful sustainable aquaculture of this commercially valuable species.
Bajek, Aline, Bossier, Peter, De Geest, Bruno, Dierckens, Kristof, Norouzitallab, Parisa, Vanrompay, Daisy, Yaacob, Eamy Nursaliza   +6 more
core   +2 more sources

Systems integration of innate and adaptive immunity [PDF]

Vaccine, 2015
The pathogens causing AIDS, malaria, and tuberculosis have proven too complex to be overcome by classical approaches to vaccination. The complexities of human immunology and pathogen-induced modulation of the immune system mandate new approaches to vaccine discovery and design.
Daniel E. Zak, Alan Aderem
openaire   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. [PDF]

, 2019
Glioblastomas (GBM) are highly infiltrated by myeloid-derived innate immune cells that contribute to the immunosuppressive nature of the brain tumor microenvironment (TME).
Gao, Peisong, Lal, Bachchu, Laterra, John, Lee, Richard S, Li, Jian Jian, Liu, Senquan, Lopez-Bertoni, Hernando, Ma, Ding, Wang, Shuyan, Wei, Shuang, Wilson, Mary Ann, Xia, Shuli, Ying, Mingyao, Zhan, Daqian, Zhang, Hao   +14 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source