Results 61 to 70 of about 1,626,946 (340)
Bacteriophage and the Innate Immune System: Access and Signaling
Microorganisms, 2019 Bacteriophage and the bacteria they infect are the dominant members of the gastrointestinal microbiome. While bacteria are known to be central to maintenance of the structure, function, and health of the microbiome, it has only recently been recognized ...
A. Carroll-Portillo, Henry C. Lin
semanticscholar +1 more source
Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System
Vaccines, 2018 Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted scientists in utilizing them as a unique tool in various applications in
Mona O. Mohsen +3 more
semanticscholar +1 more source
Bone and the Innate Immune System [PDF]
Current Osteoporosis Reports, 2014 The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Charles, Julia F, Nakamura, Mary C
openaire +4 more sources
Planarians (Platyhelminthes)—An Emerging Model Organism for Investigating Innate Immune Mechanisms
Frontiers in Cellular and Infection Microbiology, 2021 An organism responds to the invading pathogens such as bacteria, viruses, protozoans, and fungi by engaging innate and adaptive immune system, which functions by activating various signal transduction pathways. As invertebrate organisms (such as sponges,
Luis Johnson Kangale +9 more
doaj +1 more source
System of innate immunity in plants [PDF]
Molecular Biology, 2011 The review deals with the mechanisms of innate immunity in plants with a focus on families of pattern-recognition receptors and regard for recent data on complete sequencing of the genomes of several plant species. Plants utilize several families of such receptors, both membrane-bound and cytoplasmic ones, which contain conservative leucine-rich ...
O A, Vakhrusheva, S A, Nedospasov
openaire +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Probing the phenomenon of trained immunity in invertebrates during a transgenerational study, using brine shrimp Artemia as a model system [PDF]
, 2016 The invertebrate's innate immune system was reported to show some form of adaptive features, termed trained immunity. However, the memory characteristics of innate immune system and the mechanisms behind such phenomena remain unclear.
Baruah, Sri Kartik +4 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]
, 2015 Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source