CD4+CD25+ TR cells suppress innate immune pathology through cytokine-dependent mechanisms [PDF]
, 2003 Copyright @ 2003 The Rockefeller University PressCD4+CD25+ regulatory T (TR) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved.
Maloy, Kevin +19 more
core +1 more source
Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
Frontiers in Cardiovascular Medicine, 2015 The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
doaj +1 more source
Bacteriophage and the Innate Immune System: Access and Signaling
Microorganisms, 2019 Bacteriophage and the bacteria they infect are the dominant members of the gastrointestinal microbiome. While bacteria are known to be central to maintenance of the structure, function, and health of the microbiome, it has only recently been recognized ...
A. Carroll-Portillo, Henry C. Lin
semanticscholar +1 more source
Main Components of Fish Immunity: An Overview of the Fish Immune System
Fishes, 2023 Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents
Doaa M. Mokhtar +5 more
semanticscholar +1 more source
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation
Mediators of Inflammation, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj +1 more source
Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges
Frontiers in Immunology, 2017 The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
doaj +1 more source
Long‐term reprogramming of the innate immune system
Journal of Leukocyte Biology, 2018 During the last few years, a growing body of evidence has shown that immunological memory is not an exclusive trait of lymphocytes, as many inflammatory insults can alter the functionality and the responsiveness of the innate immune system in the long ...
Jorge Domínguez-Andrés, M. Netea
semanticscholar +1 more source
'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe +5 more
core +1 more source
RNA sensors of the innate immune system and their detection of pathogens
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2017 The innate immune system plays a critical role in pathogen recognition and initiation of protective immune response through the recognition of pathogen associated molecular patterns (PAMPs) by its pattern recognition receptors (PRRs).
Nanhua Chen +5 more
semanticscholar +1 more source
Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis
, 2004 Streptococcus uberis and Serratia marcescens are Gram-positive and Gram-negative bacteria, respectively, that induce clinical mastitis. Once initial host barrier systems have been breached by these pathogens, the innate immune system provides the next ...
Bannerman, Douglas +20 more
core +1 more source